Anti-RFC1 antibodies are used in the immunodetection of the protein replication factor C subunit 1. In humans, the canonical protein has a reported length of 1148 amino acid residues and a mass of 128.3 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is widely expressed across many tissue types. A member of the Activator 1 large subunit protein family, RFC1 is known to be involved with DNA repair and DNA replication. The RFC1 gene has been associated with the disease, Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome. Synonyms for this target antigen include CANVAS, MHCBFB, PO-GA, RECC1, RFC, RFC140, A1 140 kDa subunit, and A1. RFC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of RFC1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.