Anti-Angiomotin antibodies are used for the immunodetection of the protein encoded by the AMOT gene. In humans, the canonical protein has a reported length of 1084 amino acid residues and a mass of 118.1 kDa. Its subcellular localization is in the cell junctions. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the placenta and skeletal muscle. A member of the Angiomotin protein family, it is known to play an important role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Post-translational modifications have been described, including ubiquitination. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of Angiomotin antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.