Anti-IKZF3 antibodies are used in the immunodetection of the protein IKAROS family zinc finger 3. In humans, the canonical protein has a reported length of 509 amino acid residues and a mass of 58 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 16 different isoforms have been reported for this protein. It is noted to be expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus. A member of the Ikaros C2H2-type zinc-finger protein family, Ikzf3 is reported to be a transcription factor that plays an important role in the regulation of lymphocyte differentiation. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include AIOLOS, IMD84, ZNFN1A3, zinc finger protein Aiolos, zinc finger DNA binding protein Aiolos, and AIO. IKZF3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 100 citations in the literature describe the use of Ikzf3 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.