Anti-SUPT16H antibodies are used in the immunodetection of the protein SPT16 homolog, facilitates chromatin remodeling subunit. In humans, the canonical protein has a reported length of 1047 amino acid residues and a mass of 119.9 kDa. Its subcellular localization is in the nucleus and chromosomes. It is ubiquitously expressed across many tissue types. A member of the Peptidase M24 protein family, SUPT16H is a known component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The SUPT16H gene has been associated with the disease, Neurodevelopmental disorder with dysmorphic facies and thin corpus callosum. Synonyms for this target antigen include FACTP140, NEDDFAC, SPT16, SPT16/CDC68, FACT complex subunit SPT16, and CDC68. SUPT16H gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 50 citations in the literature describe the use of SUPT16H antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.