Anti-APTX antibodies are used in the immunodetection of the protein aprataxin. In humans, the canonical protein has a reported length of 356 amino acid residues and a mass of 40.7 kDa. Its subcellular localization is in the nucleus. Up to 13 different isoforms have been reported for this protein. It is reported to be widely expressed, detected in the liver, kidney and lymph node. APTX is known to be a DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Synonyms for this target antigen include AOA1, AXA1, EAOH, EOAHA, FHA-HIT, forkhead-associated domain histidine triad-like protein, and AOA. APTX gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of APTX antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.