Anti-COL6A6 antibodies are used in the immunodetection of the protein collagen type VI alpha 6 chain. In humans, the canonical protein has a reported length of 2263 amino acid residues and a mass of 247.2 kDa. Its subcellular localization is in the extracellular matrix and is also secreted. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Type VI collagen protein family, it is known to be involved with cell adhesion. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include collagen alpha-6(VI) chain and collagen, type VI, alpha 6.