Anti-SH3 and multiple ankyrin repeat domains 3 antibodies are directed against the protein encoded by the gene SHANK3 in humans. The gene may also be known as Shank 3, ProSAP2, DEL22q13. Structurally, the protein is reported to be 184.7 kilodaltons in mass. Based on gene name, canine, porcine, monkey, mouse and rat orthologs may also be found.
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