Anti-TNFAIP3 antibodies are used in the immunodetection of the protein TNF alpha induced protein 3. In humans, the canonical protein has a reported length of 790 amino acid residues and a mass of 89.6 kDa. Its subcellular localization is in the nucleus, lysosomes and cytoplasm. It is notably widely expressed in many tissue types. A member of the Peptidase C64 protein family, TNFAIP3 is reported to be a ubiquitin-editing enzyme that contains both ubiquitin ligase and deubiquitinase activities. Post-translational modifications have been described, including protein cleavage. Synonyms for this target antigen include AIFBL1, AISBL, OTUD7C, TNFA1P2, tumor necrosis factor alpha-induced protein 3, and A20. TNFAIP3 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Over 230 citations in the literature describe the use of TNFAIP3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.