Anti-PRRT2 antibodies are used in the immunodetection of the protein proline rich transmembrane protein 2. In humans, the canonical protein has a reported length of 340 amino acid residues and a mass of 34.9 kDa. Its subcellular localization is in the cell membrane. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the cerebellum and cerebral cortex. It is a member of the CD225/Dispanin protein family. The PRRT2 gene has been associated with the disease, Episodic kinesigenic dyskinesia. Synonyms for this target antigen include dispanin subfamily B member 3, dystonia 10, infantile convulsions and paroxysmal choreoathetosis, interferon induced transmembrane protein domain containing 1, and Benign familial infantile convulsions-2. PRRT2 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. A number of PRRT2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.