Anti-CTH antibodies are used in the immunodetection of the protein cystathionine gamma-lyase. In humans, the canonical protein has a reported length of 405 amino acid residues and a mass of 44.5 kDa. Its subcellular localization is in the cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the liver. A member of the Trans-sulfuration enzymes protein family, CTH is known to catalyze the last step in the trans-sulfuration pathway from L-methionine to L-cysteine in a pyridoxal-5'-phosphate (PLP)-dependent manner, which consists on cleaving the L,L-cystathionine molecule into L-cysteine, ammonia and 2-oxobutanoate. Synonyms for this target antigen include CSE, cysteine desulfhydrase, cysteine-protein sulfhydrase, gamma-cystathionase, and CGL. CTH gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 270 citations in the literature describe the use of CTH antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.