Anti-KDELR2 antibodies are used in the immunodetection of the protein KDEL endoplasmic reticulum protein retention receptor 2. In humans, the canonical protein has a reported length of 212 amino acid residues and a mass of 24.4 kDa. Its subcellular localization is in the ER, Golgi, and cytoplasmic vesicles. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the ERD2 protein family, KDELR2 is reported to be a membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi. Synonyms for this target antigen include ELP1, ERD2.2, OI21, ER lumen protein-retaining receptor 2, (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, and ELP-1. A number of KDELR2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.