Anti-PCSK5 antibodies are used in the immunodetection of the protein proprotein convertase subtilisin/kexin type 5. In humans, the canonical protein has a reported length of 1860 amino acid residues and a mass of 206.9 kDa. It has been described to be a secreted protein. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in T-lymphocytes. A member of the Peptidase S8 protein family, PCSK5 is reported to be a serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Synonyms for this target antigen include PC6, PC6A, SPC6, proprotein convertase subtilisin/kexin type 5, prohormone convertase 5, and PC5. PCSK5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PCSK5 antibodies have been mentioned in research publications and have associated citations. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.