PNKP encodes the human gene, Polynucleotide kinase 3'-phosphatase. It may also be known as: Bifunctional polynucleotide phosphatase/kinase; DNA 5'-kinase/3'-phosphatase; Polynucleotide kinase-3'-phosphatase; Polynucleotide 3'-phosphatase; 2'(3')-polynucleotidase; Polynucleotide 5'-hydroxyl-kinase; EIEE10; MCSZ; PNK. The encoded protein is an enzyme with an amino acid length of 521 and a mass of 57.1 kDa. PNKP is a member of the DNA 3' phosphatase family. Homologs of this gene exist in other organisms, including: Mouse, Fly, Rat, Zebrafish, Frog.