Anti-HLX antibodies are used in the immunodetection of the protein H2.0 like homeobox. In humans, the canonical protein has a reported length of 488 amino acid residues and a mass of 50.8 kDa. Its subcellular localization is in the nucleus. A member of the H2.0 homeobox protein family, HLX is known to be a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Synonyms for this target antigen include HLX1, H2.0-like homeobox protein, H2.0-like homeo box-1, H2.0-like homeobox 1, homeobox protein HB24, and HB24. HLX gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of HLX antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.