Anti-RAP1B antibodies are used in the immunodetection of the protein RAP1B, member of RAS oncogene family. In humans, the canonical protein has a reported length of 184 amino acid residues and a mass of 20.8 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 4 different isoforms have been reported for this protein. A member of the Ras protein family, RAP1B is reported to be a GTP-binding protein that possesses intrinsic GTPase activity. Synonyms for this target antigen include RAL1B, ras-related protein Rap-1b, GTP-binding protein smg p21B, RAS-related protein RAP1B, Ras family small GTP binding protein RAP1B, and K-REV. RAP1B gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 80 citations in the literature describe the use of RAP1B antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.