Anti-EIF6 antibodies are used in the immunodetection of the protein eukaryotic translation initiation factor 6. In humans, the canonical protein has a reported length of 245 amino acid residues and a mass of 26.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is noted to be expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in the kidney and muscle. A member of the EIF-6 protein family, EIF6 is known to bind to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Synonyms for this target antigen include EIF3A, ITGB4BP, b(2)gcn, p27(BBP), p27BBP, and CAB. EIF6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of EIF6 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.