Anti-Cbl proto-oncogene B, E3 ubiquitin protein ligase antibodies are used in antigen-specific immunodetection in biological samples. The target Cbl proto-oncogene B, E3 ubiquitin protein ligase is a known alias name of the protein Cbl proto-oncogene B, encoded by the CBLB gene in humans. This 982-amino acid residue protein is known to be involved in immune response pathways and intracellular signal transduction, among other biological processes. It is localized to the cytoplasm of the cell and features ubiquitinated and phosphorylated post-translational modifications. It is reported to be widely expressed in many tissue types. Other synonyms for Cbl proto-oncogene B, E3 ubiquitin protein ligase include Nbla00127, RNF56, and E3 ubiquitin-protein ligase CBL-B.