Understanding the Key Epigenetic Processes in Cellular Reprogramming and Pluripotency-Building Future Therapeutics

Webinar Summary/Description

The discovery of a defined set of transcription factors that can induce reprogramming of somatic cells to pluripotent stem cells (iPSCs) has had an unprecedented impact on our view on future cell transplantation-based tissue repair and restoration of faulty physiological functions. Somatic cell reprogramming is a several weeks long process through which cells reach pluripotency, the developmental state similar to embryonic stem cells. This cascade of events and the epigenetic driving forces behind the phenomenon are very poorly understood. It is, however, crucial to understand the fine details of this process in order to comprehend the true properties of iPSCs and better tailor their future use as viable therapeutic tools.

In this webinar, two leading experts in the field of cellular reprogramming and pluripotency of somatic cells will share exciting examples of their research and recent tools developed that examine the key factors that influence the reprogramming process at the epigenome, transcriptome and proteome levels.