Acro
Human Her2, His tag
HE2-H5225
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Used Octet to verify binding of Trasuzumab to Her2-his by octet. Binding was verified and this reagent was used to screen Anti-Her2 variants
Protein-Protein Interaction
N/A
NA
Immobilized Trasuzumab onto human capture biosensors, flow different concentrations of Her2-his. Dose response signal was observed, and sensorgrams were fit w/ 1:1 global model with a KD ~2nM
product was good quality.
Good quality reagent with specific binding observed. Subsequent experiments used this reagent.