Anti-human Trop2 Works Great

Biopharma
Protein Therapeutics
Lab Technician

Overall

Quality of Results

Ease-of-Optimization

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Company:

Acro

Product Name:

Human TROP-2 / TACSTD2 Protein, His Tag

Catalog Number:

TR2-H5223

Validate Anti-human Anti-Trop2 binding to Trop2. We were using the antibody to screen for binding to different Trop2 variants. We used Human TROP-2 from Acro as positive control and compared binding to this molecule by Octet.

Experimental Design and Results Summary

Application

Protein: Protein interaction

Starting Material

N/A

Tips

NA

Results Summary

The binding assay was straight forward. Immobilize Anti-human Trop2 on ProA biosensors, and flow dose response of human Trop2-his in PBS. Estimated KD was ~10nM

DOI or PMID #

N/A

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Summary

The Good

Quality was good, vendor sold the protein at >95% pure

The Bad

NA

The Bottom Line

Protein was good at binding to the antibody and having ~10nM KD

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