Invitrogen
CD152 (CTLA-4) Monoclonal Antibody-PE-eFluor 610
61-1522-82
UC10-4B9
Info: Supplier Page View Product Specs View Product
Browse Similar Products: CD152 Flow Cytometry Antibodies
As a cancer immunology lab, we study exhaustion in T cells within the tumor microenvironment. CTLA4 is a classic marker of exhaustion as it suppresses activation . Expression of this indicates highly dysfunctional T cells hence we analyze expression of this marker in our flow cytometry experiments.
Flow Cytometry
Murine tumor samples
1:400 in FACS buffer
FC Block in FACS before staining
None
Cytek Aurora (4 Laser)
Can readily detect high CTLA4 expression on the most exhausted T cells (PD1+).
Titrate before using
Very bright signal
Highly recommend this antibody for users studying exhaustion.