Time Course Effect of Chemoattractant on XPC Expression

November 14, 2019

Internal Medicine
Texas Tech University Health Science Center
Postdoctoral Researcher

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Company:

Santa Cruz Biotechnology

Product Name:

XPC antibody

Catalog Number:

sc-74410

Clone Number:

H-300

Xeroderma pigmentosum (XP), an autosomal recessive disorder caused by a genetic predisposition to sunlight-induced skin cancer due to deficiencies in the DNA repair enzymes. NER provides versatile DNA repair mechanisms to ensure the proper functioning of all cells. Here we checked the time course effect of XPC by chemoattractant.

Experimental Design and Results Summary

Applications

Western Blot

Sample

Mouse lysate

Primary Incubation

1:1000 dilution prepared in 1x TBST

Blocking Agent

5% milk with 1x TBST

Secondary Incubation

1:4000 dilution prepared in 1x TBST

Tertiary Incubation

None

Detection

ECL

Results Summary

There is no change in the XPC expression by chemoattractant.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

Image Gallery

Summary

The Good

Highly specific and strong signal

The Bad

None

The Bottom Line

This antibody works great for western blot and signal is very strong. Highly recommended.

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