Tocris Bioscience
Glibenclamide
0911/100
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Primary guinea pig ventricular cardiomyocytes were incubated with LPS for 6-10 hr. Cells were patched and stimulated at a 1 Hz frequency. Action potentials were recorded before and after glibenclamide (5 microM) containing normal tyrode solution. Glibenclamide prolonged action potential duration in LPS-treated cardiomyocytes; indicating role of KATP channels.
Cardiac electrophysiology
Guinea pig cardiomyocytes
Primary guinea pig ventricular cardiomyocytes were incubated with LPS for 6-10 hr. Cells were patched and stimulated at a 1 Hz frequency. Action potentials were recorded before and after glibenclamide (5 microM) containing normal tyrode solution.
N/A
Glibenclamide prolonged action potential duration in LPS-treated cardiomyocytes; indicating role of KATP channels.
Works as expected