BD Pharmingen
APC Mouse Anti-Human CD27
337169
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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody-secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining circulating plasmablasts (CD27++CD38+) in isolated PBMCs from peripheral blood of a healthy donor (HD). The antibody is good to stain CD27 in human peripheral B cells.
Flow Cytometry
Isolated PBMCs from HD peripheral blood
Anti CD27 APC
Fc block
N/A
It is a good antibody that allows to stain plasmablasts (CD27++) in circulation, as well as memory B cells (CD27+) and naive B cells (CD27-)
Bright
Expensive
It is a good option to stain CD27 in human peripheral B cells.