Improved gene detection from FFPE and low-input RNA
Travis Sanders, PhD
Wednesday, November 30, 2022
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Chapters
Introduction
Sequencing as the universal readout
The mission of the industry is to make the data output be a perfect representation of the information carried in the sample
The evolving clinical genomics market
Our core competencies provide the foundation
The value of vertical integration
RNA Library Prep: Problem statement
Watchmaker RNA Library Prep with Polaris Depletion
Efficiently sequence blood-derived RNA
Characterize lncRNAs: MALAT1 coverage
Increase sequencing economy and sensitivity with low-input samples
Maintain sample complexity at low inputs
Identify genes with confidence
Prevent data distortion with low-input samples
Confidently sequence across a wide input range
Improve sensitivity with FFPE samples
Identify genes with confidence
Summary
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