Bead-based Multiplex Assays for Malaria Epidemiological Estimates and Immunological Studies
Ryan Bernhardt
Monday, May 9, 2022
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Chapters
Introduction
Some Infectious Diseases are Easier to Spot than Others
The Cycle of Malaria Transmission and Human Response to Infection
The Necessity of Accurate Epidemiological Data for Malaria Programs
Methods to Collect Data on Malaria or Plasmodium Parasite Populations
Bead-based Multiplex Assays Utilizing Luminex xMAP® Technology
Detection of Plasmodium Antigens by Bead-based Multiplex Assays
HRP2 Detection to Estimate P. falciparum Infection Prevalence
Prevalence of P. vivax and P. vivax/P. falciparum Mixed Infections
Antigen Assay Results for Multiple Targets Allows Interpretation Categories
The Utility of Antibody Detection for Malaria Epidemiology and Research
More Comprehensive Immunoprofiling as Additional Targets are Added for Antibody Detection
Multiplex Serology in a Low-Transmission Setting: Haiti
Multiplex Serology in a Low-Transmission Setting: Ethiopia
Evaluating Antibody Dynamics in Convalescent P. falciparum Patients
Estimating Differences in Ig Dynamics between Primary or Repeat Malaria Exposure
Assay Deployment to Laboratories in Malaria-Endemic Settings
Conclusion
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