Description
For the Kinetic Quantitative Determination of Gamma-Glutamyl Transferase in Serum for Manual and/or Automated Procedures. Gamma-glutamyl transferase (Gamma-GT) is one of a large group of enzymes known as peptidases. Although renal tissue has the highest level of Gamma-GT, the major source of the enzyme present in serum is of hepatic origin. Elevated levels of Gamma-GT are found in association with hepatobiliary and pancreatic disorders; alcoholics and heavy drinkers, in myocardial disorders and in diabetics. Unlike alkaline phosphatase activity, the serum Gamma-GT activity remains normal in diseases affecting bone and during normal bone growth. Therefore, a rise in serum Gamma-GT activity may be considered as a sensitive and more specific indicator of liver disease than alkaline phosphatase activity.