InVivoMab anti-mouse ICOSL (CD275) BE0028-R025mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse ICOSL (CD275)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0028-R025mg
Quantity25 mg
Applicationsin vivo ICOSL neutralization
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetICOSL
IsotypeIgG2a, κ
CloneHK5.3
Hostrat
NCBI Full Gene Nameicos ligand
NCBI Gene AliasesB7-H2, B7RP-1, B7h, GI50, GL50, GL50-B, ICOS-L, Icoslg, LICOS, Ly115l, mKIAA0653
ClonalityMonoclonal
ImmunogenMouse B7-RP1 transfected cell line
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaCancer Biology, Immune Checkpoint Protein, Immunology, Innate Immunity

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Email: customerservice@bxcell.com

(1) IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with AgeJournal of immunology (Baltimore, Md. : 1950)August 1, 2015Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA.

(2) ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiationImmunityFebruary 17, 2015Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai CY, Emslie E, Lin YC, Yang E, Goldrath AW, Li MO, et al.

(3) IL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive functionJournal of immunology (Baltimore, Md. : 1950)September 1, 2014Huang W, Jeong AR, Kannan AK, Huang L, August A.

(4) Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2Proceedings of the National Academy of Sciences of the United States of AmericaJuly 22, 2014Xin L, Jiang TT, Chaturvedi V, Kinder JM, Ertelt JM, Rowe JH, Steinbrecher KA, Way SS.

(7) Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotypeImmunityMarch 21, 2013Baumjohann D, Preite S, Reboldi A, Ronchi F, Ansel KM, Lanzavecchia A, Sallusto F.

InVivoMab anti-mouse ICOSL (CD275)