InVivoMab anti-mouse OX40L (CD134L) BE0033-1-R050mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse OX40L (CD134L)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0033-1-R050mg
Quantity50 mg
Applicationsin vivo blocking of OX40/OX40L signaling, in vitro OX40L neutralization
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetOX40L
IsotypeIgG2b, κ
CloneRM134L
Hostrat
NCBI Full Gene Nametumor necrosis factor (ligand) superfamily, member 4
NCBI Gene AliasesAth-1, Ath1, CD134L, OX-40L, Ox40l, TXGP1, Tnlg2b, Txgp1l, gp34
ClonalityMonoclonal
ImmunogenRat NRK-52E cells transfected with mouse OX40L
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 7.0, Contains no stabilizers or preservatives
Research AreaImmune Checkpoint Protein, Immunology, Innate Immunity

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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Email: customerservice@bxcell.com

(1) Anti-OX40L alone or in combination with anti-CD40L and CTLA4Ig does not inhibit the humoral and cellular response to a major grass pollen allergenClinical and experimental allergy : journal of the British Society for Allergy and Clinical ImmunologyFebruary 1, 2016Gattringer M, Baranyi U, Pilat N, Hock K, Klaus C, Ramsey HE, Wrba F, Valenta R, Wekerle T.

(2) The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansioneLifeAugust 11, 2015Welten SP, Redeker A, Franken KL, Oduro JD, Ossendorp F, Čičin-Šain L, Melief CJ, Aichele P, Arens R.

(3) Effector T cells boost regulatory T cell expansion by IL-2, TNF, OX40, and plasmacytoid dendritic cells depending on the immune contextJournal of immunology (Baltimore, Md. : 1950)February 1, 2015Baeyens A, Saadoun D, Billiard F, Rouers A, Grégoire S, Zaragoza B, Grinberg-Bleyer Y, Marodon G, Piaggio E, Salomon BL.

(4) Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2Proceedings of the National Academy of Sciences of the United States of AmericaJuly 22, 2014Xin L, Jiang TT, Chaturvedi V, Kinder JM, Ertelt JM, Rowe JH, Steinbrecher KA, Way SS.

(5) Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cellsNature immunologyMay 1, 2014Mahmud SA, Manlove LS, Schmitz HM, Xing Y, Wang Y, Owen DL, Schenkel JM, Boomer JS, Green JM, Yagita H, et al.

(7) Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascadeNature communicationsJanuary 1, 2013Leyva-Castillo JM, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V, Li M.

(9) Comparison of OX40 ligand and CD70 in the promotion of CD4+ T cell responsesJournal of immunology (Baltimore, Md. : 1950)August 15, 2010Kurche JS, Burchill MA, Sanchez PJ, Haluszczak C, Kedl RM.

(10) Critical, but conditional, role of OX40 in memory T cell-mediated rejectionJournal of immunology (Baltimore, Md. : 1950)February 1, 2006Vu MD, Clarkson MR, Yagita H, Turka LA, Sayegh MH, Li XC.

InVivoMab anti-mouse OX40L (CD134L)