InVivoMab anti-mouse PD-L1 (B7-H1) BE0101-R050mg from Bio X Cell

Product Specs
ItemInVivoMab anti-mouse PD-L1 (B7-H1)
CompanyBio X Cell
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberBE0101-R050mg
Quantity50 mg
Applicationsin vivo PD-L1 blockade, Immunofluorescence, Immunohistochemistry (frozen), Flow cytometry, Western blot
ConcentrationLot specific,typically between 4-11 mg/ml
Conjugate/TagUnconjugated
ReactivityMouse
TargetPD-L1
IsotypeIgG2b, κ
Clone10F.9G2™
Hostrat
NCBI Full Gene NameCD274 antigen
NCBI Gene AliasesA530045L16Rik, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
ClonalityMonoclonal
ImmunogenMouse CD274
Antibody TypePrimary Antibody
Purity>95%, Determined by SDS-PAGE
FormatPBS, pH 6.5, Contains no stabilizers or preservatives
Research AreaCancer Biology, Immune Checkpoint Protein, Immunology, Tumor Antigens

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

39 Labombard Rd

Lebanon, NH 03766

United States

Phone: 1-866-787-3444

Email: customerservice@bxcell.com

(1) PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T CellsImmunityAugust 21, 2018Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt FA, Liniany LP, Knight D, Samsel LA, Berlinguer-Palmini R, Yim JJ, Felizardo TC, et al.

(2) The Antitumor Activity of Combinations of Cytotoxic Chemotherapy and Immune Checkpoint Inhibitors Is Model-DependentFrontiers in immunologyJanuary 1, 2018Grasselly C, Denis M, Bourguignon A, Talhi N, Mathe D, Tourette A, Serre L, Jordheim LP, Matera EL, Dumontet C.

(3) Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cellsNature communicationsJanuary 28, 2016Aloulou M, Carr EJ, Gador M, Bignon A, Liblau RS, Fazilleau N, Linterman MA.

(4) A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1Cancer researchSeptember 15, 2015Ngiow SF, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, Smyth MJ.

(5) Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 helpNature communicationsAugust 14, 2015Kim J, Jeong Ryu S, Oh K, Ju JM, Yeong Jeon J, Nam G, Lee DS, Kim HR, Young Kim J, Chang J, et al.

(6) Programmed death-1 controls T cell survival by regulating oxidative metabolismJournal of immunology (Baltimore, Md. : 1950)June 15, 2015Tkachev V, Goodell S, Opipari AW, Hao LY, Franchi L, Glick GD, Ferrara JL, Byersdorfer CA.

(7) PD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral ImmunityCell host & microbeMay 13, 2015Zander RA, Obeng-Adjei N, Guthmiller JJ, Kulu DI, Li J, Ongoiba A, Traore B, Crompton PD, Butler NS.

(8) Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancerNatureApril 16, 2015Twyman-Saint Victor C, Rech AJ, Maity A, Rengan R, Pauken KE, Stelekati E, Benci JL, Xu B, Dada H, Odorizzi PM, et al.

(9) Both PD-1 ligands protect the kidney from ischemia reperfusion injuryJournal of immunology (Baltimore, Md. : 1950)January 1, 2015Jaworska K, Ratajczak J, Huang L, Whalen K, Yang M, Stevens BK, Kinsey GR.

(11) Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in miceThe Journal of clinical investigationFebruary 1, 2014Deng L, Liang H, Burnette B, Beckett M, Darga T, Weichselbaum RR, Fu YX.

(13) Targeting the tumor microenvironment with interferon-β bridges innate and adaptive immune responsesCancer cellJanuary 13, 2014Yang X, Zhang X, Fu ML, Weichselbaum RR, Gajewski TF, Guo Y, Fu YX.

(14) Virus-induced hepatocellular carcinomas cause antigen-specific local toleranceThe Journal of clinical investigationMarch 1, 2013Willimsky G, Schmidt K, Loddenkemper C, Gellermann J, Blankenstein T.

(17) Essential role of PDL1 expression on nonhematopoietic donor cells in acquired tolerance to vascularized cardiac allograftsAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant SurgeonsApril 1, 2011Riella LV, Watanabe T, Sage PT, Yang J, Yeung M, Azzi J, Vanguri V, Chandraker A, Sharpe AH, Sayegh MH, et al.

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8/14/2017SPR Immobilization For Affinity Analysis Shubhanchi NigamOur group use ANti PDL-1 antibody as a standard to compare the affinity of newly synthesised Antibody fragments

InVivoMab anti-mouse PD-L1 (B7-H1)