InVivoMab anti-mouse TIGIT BE0274-R025mg from Bio X Cell

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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(1) TIGIT limits immune pathology during viral infectionsNature communicationsMarch 9, 2020Schorer M, Rakebrandt N, Lambert K, Hunziker A, Pallmer K, Oxenius A, Kipar A, Stertz S, Joller N.

(2) Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor ImmunityJournal of immunology (Baltimore, Md. : 1950)April 15, 2018Dixon KO, Schorer M, Nevin J, Etminan Y, Amoozgar Z, Kondo T, Kurtulus S, Kassam N, Sobel RA, Fukumura D, et al.

(3) TIGIT Enhances Antigen-Specific Th2 Recall Responses and Allergic DiseaseJournal of immunology (Baltimore, Md. : 1950)May 1, 2016Kourepini E, Paschalidis N, Simoes DC, Aggelakopoulou M, Grogan JL, Panoutsakopoulou V.

(4) Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapyNature communicationsSeptember 3, 2014Burton BR, Britton GJ, Fang H, Verhagen J, Smithers B, Sabatos-Peyton CA, Carney LJ, Gough J, Strobel S, Wraith DC.

(5) The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functionsNature immunologyMay 1, 2014Chan CJ, Martinet L, Gilfillan S, Souza-Fonseca-Guimaraes F, Chow MT, Town L, Ritchie DS, Colonna M, Andrews DM, Smyth MJ.

(7) Cutting edge: TIGIT has T cell-intrinsic inhibitory functionsJournal of immunology (Baltimore, Md. : 1950)February 1, 2011Joller N, Hafler JP, Brynedal B, Kassam N, Spoerl S, Levin SD, Sharpe AH, Kuchroo VK.

InVivoMab anti-mouse TIGIT