IL-1 beta/IL-1F2 Antibody MAB201-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-1 beta/IL-1F2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB201-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsWestern Blot, Simple Western, Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry, CyTOF-ready
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
TargetIL-1 beta/IL-1F2
IsotypeIgG1
Clone8516
HostMouse
ImmunogenE. coli-derived recombinant human IL-1 beta/IL-1F2, aa 117-269, Accession # P01584
NCBI Full Gene Nameinterleukin 1 beta
NCBI Gene AliasesIL1F2, IL1-BETA, IL-1, IL1beta
ClonalityMonoclonal
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human IL-1 beta/IL-1F2 in Western blots. Shows less than 5% cross-reactivity with recombinant mouse (rm) IL-1 beta and rpIL-1 beta and no cross-reactivity with rrIL-1 beta, rmIL-1 alpha, rhIL-1ra, rmIL-1ra, or rrIL-1 alpha

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Yersinia deploys type III-secreted effectors to evade caspase-4 inflammasome activation in human cellsmBioOctober 31, 2023Zhang J, Brodsky IE, Shin S.

(2) Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritisFrontiers in ImmunologySeptember 26, 2023Nassima Bekaddour, Nikaïa Smith, Benoit Beitz, Alba Llibre, Tom Dott, Anne Baudry, Anne-Sophie Korganow, Sébastien Nisole, Richard Mouy, Sylvain Breton, et al.Targets,Metals,Clones,Suppliers,References CD45,89Y,HI30,Fluidigm,3089003B CD38,112Cd,HIT2,Life technologies,Q22150 HLA-DR,115 In,L243,Ozyme,BLE307651 IL-1β,141 Pr,8516,R & D Systems,MAB201-100 CD27,142 Nd,O323,Ozyme,BLE302802 CD123,143 Nd,6H6,Ozyme,BLE306002 CD4,145 Nd,RPA-T4,Ozyme,BLE300516 CD8,146

(3) Yersinia Type III-Secreted Effectors Evade the Caspase-4 Inflammasome in Human CellsbioRxiv : the preprint server for biologyJune 16, 2023Zhang J, Brodsky IE, Shin S.

(4) Discovery of senolytics using machine learningNature communicationsJune 10, 2023Smer-Barreto V, Quintanilla A, Elliott RJR, Dawson JC, Sun J, Campa VM, Lorente-Macías Á, Unciti-Broceta A, Carragher NO, Acosta JC, et al.

(5) Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activationeLifeJune 27, 2022Zhu H, Chan KT, Huang X, Cerra C, Blake S, Trigos AS, Anderson D, Creek DJ, De Souza DP, Wang X, et al.polyclonal),R&D Systems,Cat#AF-200-NA,WB (1:1000) Antibody,Anti-IL-1β (mouse monoclonal),R&D Systems,Cat#MAB201100,WB (1:1000) Antibody,Anti-IL-8 (mouse monoclonal),R&D Systems,Cat#MAB208100,WB (1:1000) Antibody,Anti-IL-6

(6) Functional analysis of human circulating immune cells based on high-dimensional mass cytometrySTAR ProtocolsJune 17, 2022Xiuxing Liu, Jianjie Lv, Huishi Wang, Yingfeng Zheng, Wenru Su(1:200),BioLegend,Cat#502941 FOXP3 (1:50),BioLegend,Cat#320102 GM-CSF (1:100),BioLegend,Cat#502315 IL-1β (1:200),Novus,Cat#MAB201-100 IL-22 (1:100),Novus,Cat#AF782 IL-23 (1:100),Novus,Cat#MAB17161 ,, Biological samples,Biological

(7) Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3Cell reportsJanuary 25, 2022Li Y, Zhu Y, Feng S, Ishida Y, Chiu TP, Saito T, Wang S, Ann DK, Ou JJ.

(8) Gasdermin D mediates the maturation and release of IL-1α downstream of inflammasomesCell reportsMarch 23, 2021Tsuchiya K, Hosojima S, Hara H, Kushiyama H, Mahib MR, Kinoshita T, Suda T.

(9) NLRP3 inflammasome function and pyroptotic cell death in human placental Hofbauer cellsJournal of reproductive immunologyNovember 1, 2020Abrahams VM, Tang Z, Mor G, Guller S.

(10) Burkholderia pseudomallei triggers canonical inflammasome activation in a human primary macrophage-based infection modelPLoS neglected tropical diseasesNovember 1, 2020Lichtenegger S, Stiehler J, Saiger S, Zauner A, Kleinhappl B, Bernecker C, Schlenke P, Wagner GE, Krause K, Gastager M, et al.

(11) Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repairJournal of neuroinflammationSeptember 9, 2020Israelov H, Ravid O, Atrakchi D, Rand D, Elhaik S, Bresler Y, Twitto-Greenberg R, Omesi L, Liraz-Zaltsman S, Gosselet F, et al.

(12) Autoimmune inner ear disease patient-associated 28-kDa proinflammatory IL-1β fragment results from caspase-7-mediated cleavage in vitroJCI insightFebruary 13, 2020Pathak S, Vambutas A.

(13) Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signallingNature communicationsNovember 1, 2019Eyre R, Alférez DG, Santiago-Gómez A, Spence K, McConnell JC, Hart C, Simões BM, Lefley D, Tulotta C, Storer J, et al.

(14) HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune EnhancersCell chemical biologyMarch 21, 2019Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H.antibody,Cell signaling,Cat# 14412S Human TNFα neutralization mouse monoclonal antibody,R&D Systems,Cat# MAB201-100 Human IFNγ neutralization mouse monoclonal antibody,Thermo Fisher,Cat# 14-7318-81 Mouse IgG1 isotype

(15) Developmental induction of human T-cell responses against Candida albicans and Aspergillus fumigatusScientific reportsNovember 15, 2018Vogel K, Pierau M, Arra A, Lampe K, Schlueter D, Arens C, Brunner-Weinzierl MC.

(16) Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytesImmunologyJuly 1, 2018Uchino Y, Woodward AM, Mauris J, Peterson K, Verma P, Nilsson UJ, Rajaiya J, Argüeso P.

(17) The Vasoreparative Function of Myeloid Angiogenic Cells Is Impaired in Diabetes Through the Induction of IL1βStem CellsJune 1, 2018Chambers SEJ, O'Neill CL, Guduric-Fuchs J, McLoughlin KJ, Liew A, Egan AM, O'Brien T, Stitt AW, Medina RJ.

(18) Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammationNature communicationsApril 18, 2018Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, Grommes J, Saha P, Titova A, Ishikawa-Ankerhold H, et al.stained using a PE-conjugated, IgG1 mouse anti-human IL-1β antibody (R&D Systems, clone #8516, Cat No. MAB201-100). Western blot analysis After stimulation platelets were immediately lysed on ice using cell lysis

(19) Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial KillingCell reportsMarch 13, 2018Clancy DM, Sullivan GP, Moran HBT, Henry CM, Reeves EP, McElvaney NG, Lavelle EC, Martin SJ.

(20) Adipose Progenitor Cell Secretion of GM-CSF and MMP9 Promotes a Stromal and Immunological Microenvironment That Supports Breast Cancer ProgressionCancer researchSeptember 15, 2017Reggiani F, Labanca V, Mancuso P, Rabascio C, Talarico G, Orecchioni S, Manconi A, Bertolini F.

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(1)

11/1/2019MAB201 (R&D Systems) Binds to Recombinant Human IL-1 Beta Anonymous ReviewerThe antibody MAB201 binds human-IL1b and can be used in other assays.

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody

IL-1 beta/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (41)

Reviews

IL-1 beta/IL-1F2 Antibody from R&D Systems, a Bio-Techne Brand

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