TIM-1/KIM-1/HAVCR Antibody MAB1817-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemTIM-1/KIM-1/HAVCR Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB1817-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsWestern Blot, Flow Cytometry, ELISA Capture (Matched Antibody Pair)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
TargetTIM-1/KIM-1/HAVCR
IsotypeIgG2b
Clone222414
HostRat
ImmunogenMouse myeloma cell line NS0-derived recombinant mouse TIM-1/KIM-1/HAVCR, Tyr22-Thr212, Accession # NP_001160104
NCBI Full Gene Namehepatitis A virus cellular receptor 1
NCBI Gene AliasesKIM-1, Tim1, Timd1, TIM-1
ClonalityMonoclonal
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse TIM-1/KIM-1/HAVCR in ELISAs and Western blots. This antibody does not cross-react with recombinant human (rh) TIM-1, rmTIM-2, or rmTIM-3

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Dipeptidase-1 governs renal inflammation during ischemia reperfusion injuryScience advancesFebruary 4, 2022Lau A, Rahn JJ, Chappellaz M, Chung H, Benediktsson H, Bihan D, von Mässenhausen A, Linkermann A, Jenne CN, Robbins SM, et al.

(2) Dietary sodium modulates nephropathy in Nedd4-2-deficient miceCell death and differentiationJune 1, 2020Manning JA, Shah SS, Henshall TL, Nikolic A, Finnie J, Kumar S.

(3) Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney InjuryInternational journal of molecular sciencesApril 5, 2020Nozaki Y, Ri J, Sakai K, Niki K, Funauchi M, Matsumura I.

(4) A combination of monosodium glutamate and high-fat and high-fructose diets increases the risk of kidney injury, gut dysbiosis and host-microbial co-metabolismPloS oneJanuary 1, 2020Pongking T, Haonon O, Dangtakot R, Onsurathum S, Jusakul A, Intuyod K, Sangka A, Anutrakulchai S, Cha'on U, Pinlaor S, et al.

(5) The Role of the EGF Receptor in Sex Differences in Kidney InjuryJournal of the American Society of Nephrology : JASNSeptember 1, 2019Zhang MZ, Sasaki K, Li Y, Li Z, Pan Y, Jin GN, Wang Y, Niu A, Wang S, Fan X, et al.was purchased from Rockland Immunochemicals; rat anti–KIM-1 (a marker of kidney epithelial injury, MAB1817–100) and mouse anti–4-hydroxynonenal (a marker of oxidative stress, no. 198960) were from R&D Systems; and

(6) Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injuryThe Journal of clinical investigationJuly 2, 2018Lau A, Chung H, Komada T, Platnich JM, Sandall CF, Choudhury SR, Chun J, Naumenko V, Surewaard BG, Nelson MC, et al.

(7) Proximal tubule-derived colony stimulating factor-1 mediates polarization of renal macrophages and dendritic cells, and recovery in acute kidney injuryKidney internationalDecember 1, 2015Wang Y, Chang J, Yao B, Niu A, Kelly E, Breeggemann MC, Abboud Werner SL, Harris RC, Zhang MZ.

(8) KIM-1-mediated phagocytosis reduces acute injury to the kidneyThe Journal of clinical investigationApril 1, 2015Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV.

(9) The pathological role of IL-18Rα in renal ischemia/reperfusion injuryLaboratory investigation; a journal of technical methods and pathologyJanuary 1, 2015Yano T, Nozaki Y, Kinoshita K, Hino S, Hirooka Y, Niki K, Shimazu H, Kishimoto K, Funauch M, Matsumura I.

(10) HAVCR/KIM-1 activates the IL-6/STAT-3 pathway in clear cell renal cell carcinoma and determines tumor progression and patient outcomeCancer researchMarch 1, 2014Cuadros T, Trilla E, Sarró E, Vilà MR, Vilardell J, de Torres I, Salcedo M, López-Hellin J, Sánchez A, Ramón y Cajal S, et al.

(11) Endogenous Tim-1 (Kim-1) promotes T-cell responses and cell-mediated injury in experimental crescentic glomerulonephritisKidney internationalMay 1, 2012Nozaki Y, Nikolic-Paterson DJ, Snelgrove SL, Akiba H, Yagita H, Holdsworth SR, Kitching AR.

(12) T cell Ig domain and mucin domain 1 engagement on invariant NKT cells in the presence of TCR stimulation enhances IL-4 production but inhibits IFN-gamma productionJournal of immunology (Baltimore, Md. : 1950)April 15, 2010Kim HS, Kim HS, Lee CW, Chung DH.

(13) TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cellsBloodOctober 1, 2007Nakae S, Iikura M, Suto H, Akiba H, Umetsu DT, Dekruyff RH, Saito H, Galli SJ.

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TIM-1/KIM-1/HAVCR Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (13)

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TIM-1/KIM-1/HAVCR Antibody from R&D Systems, a Bio-Techne Brand

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