CCL8/MCP-2 Antibody MAB281-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCCL8/MCP-2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB281-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsNeutralization, ELISA Capture (Matched Antibody Pair)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman
TargetCCL8/MCP-2
IsotypeIgG1
Clone35509
HostMouse
ImmunogenE. coli-derived recombinant human CCL8/MCP-2
NCBI Full Gene NameC-C motif chemokine ligand 8
NCBI Gene AliasesHC14, MCP-2, MCP2, SCYA10, SCYA8
ClonalityMonoclonal
Brand/TrademarkR&D Systems, a Bio-Techne Brand
PurityProtein A or G purified from ascites
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human CCL8/MCP-2 in ELISAs and Western blots. In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombinant human (rh) CCL15 and rmCCL3

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cellsbioRxiv : the preprint server for biologyFebruary 13, 2023Parween F, Singh SP, Zhang HH, Kathuria N, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, Lorenzi HA, et al.

(2) A Toll-like receptor-1 variant and its characteristic cellular phenotype is associated with severe malaria in Papua New Guinean childrenGenes and immunityJanuary 1, 2016Manning L, Cutts J, Stanisic DI, Laman M, Carmagnac A, Allen S, O'Donnell A, Karunajeewa H, Rosanas-Urgell A, Siba P, et al.

(3) Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophagesThe Journal of allergy and clinical immunologyApril 1, 2014Karta MR, Wickert LE, Curran CS, Gavala ML, Denlinger LC, Gern JE, Bertics PJ.

(4) Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effectsEuropean journal of immunologyMarch 1, 2009Struyf S, Proost P, Vandercappellen J, Dempe S, Noyens B, Nelissen S, Gouwy M, Locati M, Opdenakker G, Dinsart C, et al.

(5) Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritisAnnals of the rheumatic diseasesMarch 1, 2006Haringman JJ, Smeets TJ, Reinders-Blankert P, Tak PP.

(6) Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine productionTransplantationOctober 15, 2004Tay SS, McCormack A, Rose ML.

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CCL8/MCP-2 Antibody

CCL8/MCP-2 Antibody

CCL8/MCP-2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (6)

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CCL8/MCP-2 Antibody from R&D Systems, a Bio-Techne Brand

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