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Anti-Progerin antibody [13A4]
Anti-Progerin antibody [13A4] from Abcam
Be the first to write a review!
Citations:
(18)
Supplier Page
Supplier Page from
Abcam for
Anti-Progerin antibody [13A4]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Progerin antibody [13A4]
Company
Abcam
Price
Pricing Info
Supplier Page
View Company Product Page
Catalog Number
ab66587
Antibody Type
Primary
Quantity
10 UG, 100 UG
Isotype
IgG1
Host
Mouse, Nude mouse
Clonality
Monoclonal
Applications
Western blot
Clone
13A4
Conjugate/Tag
Unconjugated
Concentration
1 mg/ml
Research Area
Epigenetics
Gene Name
LMNA
Reactivity
Human
Target
Progerin
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (18)
(1)
Unique progerin C-terminal peptide ameliorates Hutchinson-Gilford progeria syndrome phenotype by rescuing BUBR1
Nat Aging
February 1, 2023
Zhang N, Hu Q, Sui T, Fu L, Zhang X, Wang Y, Zhu X, Huang B, Lu J, Li Z,
et al
.
anti-lamin A
/C
1:3,000
(
Abcam
, catalog no.
ab108595
), anti-progerin (13A4)
1:1,000
(
Abcam
, catalog no.
ab66587
), anti-P-H3 (S10)
1:1,000
(Cell Signaling Technology (
CST
), catalog no.
3377
), anti-H3K9me3
1:10,000
(2)
Anti-hsa-miR-59 alleviates premature senescence associated with Hutchinson-Gilford progeria syndrome in mice
The EMBO journal
January 4, 2023
Hu Q, Zhang N, Sui T, Li G, Wang Z, Liu M, Zhu X, Huang B, Lu J, Li Z,
et al
.
siCDK7#1_rev (5′‐ UUCUAAUCCUUGAAGAGUCTT‐3′). The following antibodies were used: antibodies against progerin (
ab66587
;
Abcam
);
HMGA1
(#
7777
for WB
;
Cell Signaling Technology
,
ab4078
for ChIP; and
ab129153
for IHC
;
Abcam
);
(3)
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
Nucleic Acids Research
September 23, 2022
Scott Maynard et al.
α-tubulin (
ab4074
,
Abcam
), Histone H3 (
ab1791
,
Abcam
), lamin A/C (
sc-20681
;
Santa Cruz
), progerin (
ab66587
;
Abcam
), PAR (
ab14460
;
Abcam
), SIRT1 (
04-1557
;
Millipore
), PGC1α (
NBP1-04676ss
;
Novus
),
NAMPT
(
A0256
;
(4)
Mesenchymal stem cells derived from patients with premature aging syndromes display hallmarks of physiological aging
Life science alliance
September 14, 2022
Trani JP, Chevalier R, Caron L, El Yazidi C, Broucqsault N, Toury L, Thomas M, Annab K, Binetruy B, De Sandre-Giovannoli A,
et al
.
prepared in 5% milk in PBS-T, anti-lamin A/C (
1:100
,
Sc6215
;
Santa Cruz
), and anti-progerin (
1:100
,
ab66587
;
Abcam
).
Membranes
were washed in PBS-T (4 × 5 min) and then incubated 1 h at RT with secondary antibodies
(5)
Vascular senescence in progeria: role of endothelial dysfunction
Eur Heart J Open
July 1, 2022
Xu Q, Mojiri A, Boulahouache L, Morales E, Walther BK, Cooke JP.
were analysed by using Image-J software. Primary antibodies included the following: progerin (
Abcam
#
ab66587
), histone H1 (Abcam #61177), HP1α (Cell Signalling #
2616s
),
TRF1
(
Novus
#
NB110-68281
),
TRF2
(
Novus
#
NB110-57130
),
(6)
Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A
Scientific reports
April 27, 2021
Kang SM, Yoon MH, Lee SJ, Ahn J, Yi SA, Nam KH, Park S, Woo TG, Cho JH, Lee J,
et al
.
(
1:10,000
;
sc-376248
;
Santa Cruz Biotechnology
), progerin (
1:300
;
sc-81611
;
Santa Cruz Biotechnology
and
ab66587
;
Abcam
, Cambridge, UK), Ki67 (
1:400
;
ab15580
;
Abcam
), H3K9me3 (
1:400
and
1:2000
;
ab8898
;
Abcam
), p16-INK4A
(7)
Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome
Communications biology
January 4, 2021
Kang SM, Yoon MH, Ahn J, Kim JE, Kim SY, Kang SY, Joo J, Park S, Cho JH, Woo TG,
et al
.
Santa Cruz Biotechnology
), anti-Progerin (
1:100
;
sc-81611
;
Santa Cruz Biotechnology
),
anti-Progerin
(
1:300
;
ab66587
;
Abcam
, Cambridge, UK), anti-Ki67 (
1:200
;
Ab15580
;
Abcam
), anti-cyclin B1 (
1:100
;
sc-594
;
Santa Cruz Biotechnology
(8)
Lamin A-mediated nuclear lamina integrity is required for proper ciliogenesis
EMBO reports
October 5, 2020
Fan JR, You LR, Wang WJ, Huang WS, Chu CT, Chi YH, Chen HC.
awaits for future research efforts. Materials and Methods Antibodies and reagents The anti‐progerin (
ab66587
),
anti‐lamin A
(
ab8980
), anti‐aquaporin 1 (
ab65837
), anti‐Arl3b (
ab136648
), and anti‐pericentrin (
ab4448
)
(9)
Upregulation of the aging related LMNA splice variant progerin in dilated cardiomyopathy
PloS one
January 1, 2018
Messner M, Ghadge SK, Goetsch V, Wimmer A, Dörler J, Pölzl G, Zaruba MM.
glass slides.
For Immunohistochemistry
staining
, deparaffinized sections were incubated with progerin antibody (
ab66587
,
Abcam
) followed by Vectastain Elite ABC kit (
AK-5000
,
Vector laboratories
, Cambridgeshire, UK) and
(10)
One week of exposure to sunlight induces progerin expression in human skin
Advances in Dermatology and Allergology/Post?py Dermatologii i Alergologii
December 31, 2017
Aleksandra Lesiak, Igor Bednarski, Michal Rogowski-Tylman, Michal Sobjanek, Anna Wozniacka, Marian Danilewicz, Anthony Young, Joanna Narbutt
(11)
Antisense-Based Progerin Downregulation in HGPS-Like Patients’ Cells
Cells
July 11, 2016
Karim Harhouri, Claire Navarro, Camille Baquerre, Nathalie Da Silva, Catherine Bartoli, Frank Casey, Guedenon Koffi Mawuse, Yassamine Doubaj, Nicolas Lévy, Annachiara De Sandre-Giovannoli
polyclonal anti-Lamin A/C (
sc-6215
,
Santa Cruz Biotechnology
),
1:1000
mouse
monoclonal
anti-Progerin
(
ab66587
,
Abcam
, Cambridge, UK),
1:1000
mouse
monoclonal anti-actin (
MAB1501
,
Merck Millipore
, Darmstadt, Germany)
(12)
Mutant lamin A links prophase to a p53 independent senescence program
Cell cycle (Georgetown, Tex.)
August 3, 2015
Olga Moiseeva, Frédéric Lessard, Mariana Acevedo-Aquino, Mathieu Vernier, Youla S Tsantrizos, Gerardo Ferbeyre
(13)
Truncated prelamin A expression in HGPS-like patients: a transcriptional study
European Journal of Human Genetics
August 1, 2015
Florian Barthélémy et al.
used were
goat
anti-lamin A/C (
SC-6215
;
Santa Cruz Biotechnology
, CA, USA) and
mouse
anti-progerin (
ab66587
;
Abcam
, Paris, France), respectively used at 1/100 and 1/50 dilutions. The secondary antibody used was,
(14)
Restoring SIRT6 Expression in Hutchinson-Gilford Progeria Syndrome Cells Impedes Premature Senescence and Formation of Dysmorphic Nuclei
Pathobiology
January 1, 2015
Helal Endisha, Jacqueline Merrill-Schools, Min Zhao, Molly Bristol, Xu Wang, Nard Kubben, Lynne W. Elmore
antibodies: rabbit anti-
SIRT6
(No.
2590
;
Cell Signaling Technology
);
mouse
anti-progerin antibody (
ab66587
;
Abcam
) or
mouse
monoclonal anti-β-actin (
sc-47778
;
Santa Cruz Biotechnology
), as recommended by the
(15)
Antisense oligonucleotide induction of progerin in human myogenic cells
PloS one
January 1, 2014
Yue-Bei Luo, Chalermchai Mitrpant, Abbie M Adams, Russell D Johnsen, Sue Fletcher, Frank L Mastaglia, Steve D Wilton
(16)
Longwave UV light induces the aging-associated progerin
The Journal of investigative dermatology
July 1, 2013
Hirotaka Takeuchi, Thomas M Rünger
(17)
Investigation of age-related changes in LMNA splicing and expression of progerin in human skeletal muscles
International journal of clinical and experimental pathology
January 1, 2013
Yue-Bei Luo, Chalermchai Mitrpant, Russell D Johnsen, Victoria A Fabian, Sue Fletcher, Frank L Mastaglia, Steve D Wilton
(18)
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
Nature
April 14, 2011
Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C,
et al
.
obtained from the following sources.
Abcam
: anti-NANOG (
ab21624
), anti-H3K9Me3 (
ab8898
), anti-progerin (
ab66587
), anti-emerin (ab14208); anti-Ku70 (
ab2172
);
Santa Cruz Biotechnology
: anti-Oct-3/4 (
sc-5279
), anti-SOX2
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Anti-Progerin antibody [13A4] from Abcam
Supplier Page
View Company Product Page
Pricing Info
Product Specs
Company Info
Citations
Reviews
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