Anti-IL-6R antibody [AP-MAB0848] ab83053 from Abcam

Product Specs
ItemAnti-IL-6R antibody [AP-MAB0848]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab83053
Antibody TypePrimary
Quantity500 UG
ClonalityMonoclonal
HostRat
CloneAP-MAB0848
Conjugate/TagUnconjugated
IsotypeIgG2b
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Inhibition Assay
FormatThe IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 µm filtered solution in phosphate buffered saline
Concentration1 mg/ml
Research AreaImmuno-oncology
Gene NameIl6r
ReactivityMouse
TargetIL-6R

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) miR-204-containing exosomes ameliorate GVHD-associated dry eye diseaseScience advancesJanuary 14, 2022Zhou T, He C, Lai P, Yang Z, Liu Y, Xu H, Lin X, Ni B, Ju R, Yi W, et al.(CST)], anti–annexin A1 antibody (3299, CST), anti-HSP90 antibody (4877, CST), anti–IL-6R antibody (ab83053, Abcam, MA), anti-Stat3 antibody and anti-p-Stat3 antibody (9139S and 9145S, CST), anti–IL-6 antibody

(2) Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexiaThe Journal of experimental medicineJune 7, 2021Rupert JE, Narasimhan A, Jengelley DHA, Jiang Y, Liu J, Au E, Silverman LM, Sandusky G, Bonetto A, Cao S, et al.and incubated with the primary antibodies against dystrophin (1:100; MANDRA11; DSHB), IL6R (1:500; ab83053; Abcam), and CD31 (1:500; ab24590; Abcam) diluted in blocking buffer overnight at 4°C in a humid chamber.

(3) Interleukin-6 deficiency modulates testicular function by increasing the expression of suppressor of cytokine signaling 3 (SOCS3) in miceScientific reportsJune 1, 2021Alves-Silva T, Freitas GA, Húngaro TGR, Arruda AC, Oyama LM, Avellar MCW, Araujo RC.nitrocellulose membrane. The membranes were blocked with 1% BSA for 2 h at room temperature. The primary antibodies for IL6R (ab83053, Abcam), pJAK1 (ab138005, Abcam), JAK1 (ab47435, Abcam), pSTAT3 (ab76315, Abcam), STAT3 (ab31370, Abcam)

(4) Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathwayJournal of AnesthesiaJune 1, 2021Haibin Cui, Qian Zhangno,Manufacturer IL-1β,1:2000,sc7884,"Santa Cruz Biotechnology, USA" TNF-α,1:2000,ab8348,"Abcam, UK" IL-6,1:1000,ab83053,"Abcam, UK" IL-10,1:2000,ab9969,"Abcam, UK" MDA5,1:200,ab69983,"Abcam, UK" IREα,1:2000,3294,"Abcam,

(5) Molecular Response of Skin to Micromachining by Femtosecond LaserFrontiers in PhysicsFebruary 16, 2021Yutong Wang, Shaoyang Wang, Yujie Zhu, Hui Xu, Hao Hepolyclonal anti-MMP9, 1:200, Proteintech, 10375-2-AP), and IL-6 (rat monoclonal anti-IL6R, 1:100, Abcam, ab83053) and TGF-β (rabbit polyclonal anti- TGF-β, 1:200, Proteintech, 21898-1-AP). Then the sections were washed

(6) Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASHNature communicationsJanuary 4, 2021Dong J, Viswanathan S, Adami E, Singh BK, Chothani SP, Ng B, Lim WW, Zhou J, Tripathi M, Ko NSJ, et al.(flow cytometry, ab222101, Abcam, 1:100), IL6R (human, IHC and IF, MA1-80456, Thermo Fisher, 1:100), IL6R (mouse, ab83053, Abcam, 1:100), IL11 (X203, Aldevron), IL11RA (inhibition study, X209, Aldevron), IL11RA (IHC, IF, flow cytometry

(7) Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in miceMolecular Medicine ReportsNovember 6, 2019Weiqing Hu, Wenyue Wang, Qing Ma, Tao Liu, Jiefeng Zhang, Jicun Zhangfor 1 h. The following primary antibodies were used: TNF‑ α (1:2,000; ab8348; Abcam), IL‑6 (1:1,000; ab83053; Abcam), IRE α (1:2,000; 3294; Abcam), MDA5 (1:200; ab69983; Abcam), ANP (1:500; ab251006; Abcam), BNP

(8) CD28 Deficiency Ameliorates Blast Exposure-Induced Lung Inflammation, Oxidative Stress, Apoptosis, and T Cell Accumulation in the Lungs via the PI3K/Akt/FoxO1 Signaling PathwayOxidative Medicine and Cellular LongevitySeptember 2, 2019Yunen Liu et al.following: TNF-α (1 : 2000, ab8348, Abcam, UK), IL-10 (1 : 2000, ab9969, Abcam, UK), IL-6 (1 : 1000, ab83053, Abcam, UK), IREα (1 : 2000, #3294, Abcam, UK), and MDA5 (1 : 200, ab69983, Abcam, UK). IL-1β (1 : 2000,

(9) MicroRNA‑let‑7a inhibition inhibits LPS‑induced inflammatory injury of chondrocytes by targeting IL6RMolecular Medicine ReportsJuly 12, 2019Cong Sui, Lecheng Zhang, Yong Humilk at room temperature for 2 h. Membranes were then incubated with primary antibodies: IL‑6R (cat. no. ab83053; 1:1,000; Abcam), STAT3 (cat. no. ab119352; 1:1,000; Abcam), phosphorylated STAT3 (cat. no. ab76315;

(10) Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse modelExperimental Biology and MedicineJuly 10, 2018Changci Tong, Yunen Liu, Yubiao Zhang, Peifang Cong, Xiuyun Shi, Ying Liu, Lin Shi Hongxu Jin, Mingxiao Hou(1:1000; cat. no. sc-73318; Santa Cruz Biotechnology, Inc., Dallas, TX, USA), IL-6 (1:1000; cat. no. ab83053; Abcam, Cambridge, UK), IL-10 (1:2000; cat. no. ab9969; Abcam, Cambridge, UK), MDA5 (1:1000; cat. no.

(11) Interleukin-6 Mediates Post-Infarct Repair by Cardiac Explant-Derived Stem CellsTheranosticsOctober 17, 2017Audrey E Mayfield, Pushpinder Kanda, Alex Nantsios, Sandrine Parent, Seth Mount, Somya Dixit, Bin Ye, Richard Seymour, Duncan J Stewart, Darryl R DavisTechnology). Effects of EDC-sourced IL-6 on cardiac fibroblast and macrophage function IL-6Rα expression (ab83053, Abcam) was evaluated in discoidin domain receptor 2+ (DDR2; ab76967, Abcam) CFs using immunohistochemistry.

(12) Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic AneurysmBioMed Research InternationalMarch 5, 2017Tong Jiao, Ye Yao, Bo Zhang, Da-Cheng Hao, Qing-Feng Sun, Jing-Bo Li, Chao Yuan, Bao Jing, Yun-Peng Wang, Hai-Yang Wang(Abcam, ab25088), rabbit polyclonal to TNF-α antibodies (Abcam, ab9739), rat monoclonal to IL6R (Abcam, ab83053), and rabbit monoclonal to VE-cadherin (Abcam, ab205336) were used as the primary antibodies, followed

(13) Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammationBiology of Sex DifferencesDecember 1, 2016Vikas Mishra, Susan L. DiAngelo, Patricia Silveyra

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Anti-IL-6R antibody [AP-MAB0848] from Abcam

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Anti-IL-6R antibody [AP-MAB0848] from Abcam

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