MVP Antibody / Major Vault Protein [Mouse Monoclonal] V3043 from NSJ Bioreagents

Description

MVP is required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases

Product Specs
ItemMVP Antibody / Major Vault Protein [Mouse Monoclonal]
CompanyNSJ Bioreagents
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberV3043
Quantity20 ug, 100 ug, 100 ug (azide-free), 7 ml IHC only (if applicable)
ApplicationsIHC-P
Concentration0.2 mg/ml, 1 mg/ml (BSA/azide-free format)
Conjugate/TagUnconjugated
Format0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; 1 mg/ml in 1X PBS; BSA free, sodium azide free
ReactivityHuman
IsotypeIgG1 kappa
Clone1032
HostMouse
ImmunogenProteins precipitated from human breast cancer MCF-7 cells were used as the immunogen for the Major Vault Protein antibody
NCBI Full Gene Namemajor vault protein
NCBI Gene AliasesLRP, VAULT1
ClonalityMonoclonal
PurityProtein G affinity chromatography
Antibody TypePrimary
Regulatory StatusThis Major Vault Protein antibody is available for research use only
TargetMVP

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NSJ Bioreagents

9921 Carmel Mountain Rd

#352

San Diego, CA 92129

United States

Phone: 1 (858) 663-9055

Email: info@nsjbio.com

Company Profile

Website: www.nsjbio.com

(1) Major vault protein may affect nonhomologous end-joining repair and apoptosis through Ku70/80 and bax downregulation in cervical carcinoma tumorsInternational journal of radiation oncology, biology, physicsMarch 15, 2009Lloret M, Lara PC, Bordón E, Fontes F, Rey A, Pinar B, Falcón O.

(2) Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cellThe Journal of cell biologyJune 15, 1998Abbondanza C, Rossi V, Roscigno A, Gallo L, Belsito A, Piluso G, Medici N, Nigro V, Molinari AM, Moncharmont B, et al.

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MVP Antibody / Major Vault Protein [Mouse Monoclonal]

MVP Antibody / Major Vault Protein [Mouse Monoclonal]

MVP Antibody / Major Vault Protein [Mouse Monoclonal] from NSJ Bioreagents

Description

NSJ Bioreagents

Citations (2)

Reviews

MVP Antibody / Major Vault Protein [Mouse Monoclonal] from NSJ Bioreagents

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