Anti-Pancreatic Polypeptide antibody ab77192 from Abcam

Product Specs
ItemAnti-Pancreatic Polypeptide antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab77192
Antibody TypePrimary
HostGoat
Quantity100 UG
Conjugate/TagUnconjugated
IsotypeIgG
ClonalityPolyclonal
ApplicationsELISA, Flow Cytometry, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
FormatPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Concentration0.5 mg/ml
Gene NamePPY
ReactivityHuman
TargetPancreatic Polypeptide

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometryCell reportsNovember 2, 2021Wu M, Lee MYY, Bahl V, Traum D, Schug J, Kusmartseva I, Atkinson MA, Fan G, HPAP Consortium, Kaestner KH.(UCHL1),Fluidigm,Cat#3173016D 174Yb-HLA-DR (Clone TAL 1B5),Abcam,Cat#ab20181; RRID: AB_445401 175Lu-Pancreatic Polypeptide,Abcam,Cat#ab77192; RRID: AB_1524152 176Yb-Ghrelin,Santa Cruz,Cat#sc-10368; RRID: AB_2232479 ,, Biological samples,, ,, organ

(2) Pre-existing beta cells but not progenitors contribute to new beta cells in the adult pancreasNature MetabolismMarch 15, 2021Huan Zhao, Xiuzhen Huang, Zixin Liu, Wenjuan Pu, Zan Lv, Lingjuan He, Yan Li, Qiao Zhou, Kathy O. Lui, Bin Zhou(Santa Cruz, sc-47707, 1:500), Somatostatin (Abcam, ab-111912, 1:500), Pancreatic polypeptide (Abcam, ab77192, 1:500), Pancreatic polypeptide (Abcam, ab255827, 1:500), E-cadherin (Cell Signaling, 3195, 1:500),

(3) Pancreatic cancer triggers diabetes through TGF-β-mediated selective depletion of islet β-cellsLife science allianceJune 1, 2020Parajuli P, Nguyen TL, Prunier C, Razzaque MS, Xu K, Atfi A.Cell Signaling Technology), JunB (3753; Cell Signaling Technology), Mucin5AC (MA5-12178; Thermo Fisher Scientific), PP (ab77192; Abcam), Phospho-Smad2 (3101; Cell Signaling Technology), Phospho-Smad2 (8828; Cell Signaling Technology),

(4) Heterogeneous expression of CFTR in insulin-secreting β-cells of the normal human isletPloS oneJanuary 1, 2020Di Fulvio M, Bogdani M, Velasco M, McMillen TS, Ridaura C, Kelly L, Almutairi MM, Kursan S, Sajib AA, Hiriart M, et al.considered specific" Synaptophysin (ab8049),Abcam,1:200,IF/IHC,"Widely used, considered specific" PP (ab77192),Abcam,1:250,IF/IHC,"Widely used, considered specific" E-cadherin (ab6528),Abcam,1:100,IF,Widely used Actin

(5) Long-Term Liraglutide Administration Induces Pancreas Neogenesis in Adult T2DM MiceCell transplantationJanuary 1, 2020Deng H, Yang F, Ma X, Wang Y, Chen Q, Yuan L.(NBP1-97308; Novus, CO, USA), mouse antisomatostatin (sc-74556; Santa Cruz), goat antipancreatic polypeptide (Ab77192; Abcam), rabbit anti-Ki67 (ARG53222; Arigo, Taiwan, China), rabbit anti-pancreatic and duodenal homeobox

(6) Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 DiabetesCell metabolismMarch 5, 2019Wang YJ, Traum D, Schug J, Gao L, Liu C, HPAP Consortium., Atkinson MA, Powers AC, Feldman MD, Naji A, et al.UCHL1),Fluidigm,Cat#3173016D HLA-DR (Clone TAL 1B5),Abcam,Cat#ab20181; RRID: AB_445401 PANCREATIC POLYPEPTIDE,Abcam,Cat#ab77192; RRID: AB_1524152 GHRELIN,Santa Cruz,Cat#sc-10368; RRID: AB_2232479 Software and Algorithms,, CellProfiler

(7) Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cellsScientific reportsOctober 18, 2018Azzarelli R, Rulands S, Nestorowa S, Davies J, Campinoti S, Gillotin S, Bonfanti P, Göttgens B, Huch M, Simons B, et al.glucagon (mouse, 1:200, Abcam ab10988), Somatostatin (rabbit, 1:200, Dako A0566), PPY (goat, 1:200, Abcam ab77192), ghrelin (rat, 1:50, R&D System MAB8200-SP), GFP (chicken, 1:600, Abcam ab13970), dsRed (mouse, 1:100,

(8) Lineage dynamics of murine pancreatic development at single-cell resolutionNature communicationsSeptember 25, 2018Byrnes LE, Wong DM, Subramaniam M, Meyer NP, Gilchrist CL, Knox SM, Tward AD, Ye CJ, Sneddon JB.sc-7819, Ghrelin (1:1500, Santa Cruz Biotechnology sc-10368), Pancreatic Polypeptide (PP; 1:250, Abcam ab77192), and Vimentin (1:200, Abcam ab92547). All antibodies have been validated by manufacturer. Sections

(9) MafB Is Critical for Glucagon Production and Secretion in Mouse Pancreatic α Cells In VivoMolecular and Cellular BiologyApril 15, 2018Megumi C. Katoh, Yunshin Jung, Chioma M. Ugboma, Miki Shimbo, Akihiro Kuno, Walaa A. Basha, Takashi Kudo, Hisashi Oishi, Satoru Takahashirabbit anti-pancreatic polypeptide (1:1,000; ab113694; Abcam), goat anti-pancreatic polypeptide (1:50; ab77192; Abcam), and rabbit antisomatostatin (1:50; 18-007; Zymed). Antigens were visualized using appropriate

(10) Sitagliptin and Roux-en-Y gastric bypass modulate insulin secretion via regulation of intra-islet PYYDiabetes, Obesity and MetabolismMarch 1, 2018Claudia Guida, Laura J. McCulloch, Mahdieh Godazgar, Sam D. Stephen, Charlotte Baker, Davide Basco, Jiawen Dong, Duan Chen, Anne Clark, Reshma D RamracheyaSigma, Gillingham, UK), somatostatin (sc‐25262, Santa Cruz, Insight Biotechnologies, Wembley, UK), PP (ab77192), NPY1R (ab91262, Abcam, Cambridge, UK), NPY2R (ab31894, Abcam), NPY4R (HPA027863, Sigma), NPY5R (ab32886,

(11) Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine DifferentiationDevelopmental CellMay 8, 2017Roberta Azzarelli et al.anti-glucagon,Abcam,ab10988; RRID: AB_297642 Rabbit anti-somatostatin,Dako,A0566; RRID: AB_10013726 Goat anti-PPY,Abcam,ab77192; RRID: AB_1524152 Goat anti-Ngn3,Santa Cruz Biotechnology,sc-13793; RRID: AB_650136 Mouse anti-Ngn3,DSHB,F25A1B3;

(12) Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survivalMolecular and Cellular EndocrinologyNovember 1, 2016Dawood Khan, Srividya Vasu, R. Charlotte Moffett, Nigel Irwin, Peter R. Flattab6995 Glucagon Guinea pig 1:200 Raised in-house PCA2/4 PYY Rabbit 1:500 Abcam, ab22663 PP Goat 1:200 Abcam, ab77192 SST Rat 1:500 Biorad, 8330-009 Ki67 Rabbit 1:200 Abcam, ab15580 Secondary antibodies Target Host Reactivity Dilution Fluorescent

(13) Single-Cell Mass Cytometry Analysis of the Human Endocrine PancreasCell MetabolismOctober 1, 2016Yue J. Wang et al.

(14) Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genesMolecular metabolismMarch 1, 2016Amanda M Ackermann, Zhiping Wang, Jonathan Schug, Ali Naji, Klaus H Kaestner180067], rabbit anti-somatostatin [Santa Cruz sc-13099], goat anti-pancreatic polypeptide [PP; Abcam ab77192], and goat anti-ghrelin [Santa Cruz sc-10368]; all 1:100) were incubated overnight at 4 °C, and secondary

(15) Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin SensitivityDiabetesFebruary 1, 2016Wiedemann T, Bielohuby M, Müller TD, Bidlingmaier M, Pellegata NS.(1:350), glucagon (A0565; Dako) (1:1,500), insulin (A0564; Dako) (1:750), pancreatic polypeptide (PP) (ab77192; Abcam) (1:150), and somatostatin (sc7819; Santa Cruz Biotechnology) (1:300). Primary antibodies were

(16) Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreasPloS oneJanuary 1, 2013Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, et al.

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Anti-Pancreatic Polypeptide antibody from Abcam

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Anti-Pancreatic Polypeptide antibody from Abcam

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