CD4 Alexa Fluor 488-conjugated Antibody FAB8165G from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCD4 Alexa Fluor 488-conjugated Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberFAB8165G
ReactivityHuman (Hu)
FormatSupplied in a saline solution containing BSA and Sodium Azide
ImmunogenS. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD4, Lys26-Trp390, Accession # P01730
PurityAntigen Affinity-purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageProtect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
ClonalityPolyclonal
NCBI Gene AliasesCD4mut, Leu-3, IMD79, T4, OKT4D
NCBI Full Gene NameCD4 molecule
ApplicationsFCM, ICC
HostGoat
IsotypeIgG
TargetCD4
Conjugate/TagAlexa Fluor 488
Quantity100 Tests

Specifications/Features

Available conjugates: Alexa Fluor 488

Specificity: Detects human CD4 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse CD4, recombinant feline CD4, recombinant cotton rat CD4, and recombinant canine CD4 is observed

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) ChipCytometry for multiplexed detection of protein and mRNA markers on human FFPE tissue samplesSTAR protocolsJune 17, 2022Jarosch S, Köhlen J, Wagner S, D'Ippolito E, Busch DH.4°C,Surface CD103,AF488,FS488,EPR4166(2),abcam,ab225152,1:100,o.n. 4°C,Surface CD4,AF488,FS488,polyclonal,R&D systems,FAB8165G,1:50,o.n. 4°C,Surface CD68,FITC,FS488,KP1,Santa-Cruz,sc-20060 FITC,1:100,o.n. 4°C,Surface Collagen IV

(2) Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeysCell reportsJanuary 4, 2022Pegu A, Xu L, DeMouth ME, Fabozzi G, March K, Almasri CG, Cully MD, Wang K, Yang ES, Dias J, et al.conjugated anti-CD20 (eBiosciences, clone L26) and AlexaFlour700 conjugated anti-CD4 (R&D Systems, cat. FAB8165G, goat polyclonal). After an additional wash step, the slides were counterstained for nuclear staining

(3) Multiplexed imaging and automated signal quantification in formalin-fixed paraffin-embedded tissues by ChipCytometryCell Rep MethodsNovember 22, 2021Jarosch S, Köhlen J, Sarker RSJ, Steiger K, Janssen KP, Christians A, Hennig C, Holler E, D'Ippolito E, Busch DH.antibodies ,,,,,,,,, Pan-cytokeratin,AF488,FS488,C11,mouse,BioLegend,628608,1:100,o.n. 4°C,intracellular CD4,AF488,FS488,polyclonal,Goat,R&D Systems,FAB8165G,1:50,o.n. 4°C,surface CD14,AF488,FS488,EPR3653,rabbit,Abcam,ab133335,1:100,o.n. 4°C,surface CD68,FITC,FS488,KP1,mouse,Santa Cruz

(4) Antigen dominance hierarchies shape TCF1(+) progenitor CD8 T cell phenotypes in tumorsCellSeptember 16, 2021Burger ML, Cruz AM, Crossland GE, Gaglia G, Ritch CC, Blatt SE, Bhutkar A, Canner D, Kienka T, Tavana SZ, et al.αSMA,Abcam,Clone EPR5368; Cat# ab202509; RRID: AB_2868435 tCycif: anti-human CD4,R&D Systems,Cat# FAB8165G; RRID: AB_2728839 tCycif: anti-human CD8α,ThermoFisher Scientific,Clone AMC908; Cat# 50-0008-80; RRID:

(5) Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapyCellSeptember 2, 2021Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, et al.AMC908),eBioscience,Cat# 50–0008-80; RRID: AB_2574148 Goat Polyclonal Alexa Fluor 488 anti-CD4,R&D Systems,Cat# FAB8165G; RRID: AB_2728839 Rabbit polyclonal anti-PD-L1,Novus,Cat# NBP1–76769; RRID: AB_11024101 Mouse monoclonal

(6) Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancerNature CancerMarch 19, 2021Anita K. Mehta et al.Fluor 647,Abcam,EPR4877(2),ab201825,1:200 Cycle 6,FITC,CD4–488,Alexa Fluor 488,R&D Systems,Polyclonal,FAB8165G,1:200 Cycle 6,Cy3,Ki67–570,eFluor 570,eBioscience,20Raj1,41–5699-80,1:200 Cycle 6,Cy5,PDL1–647,Alexa

(7) Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancerScientific dataDecember 17, 2019Rashid R, Gaglia G, Chen YA, Lin JR, Du Z, Maliga Z, Schapiro D, Yapp C, Muhlich J, Sokolov A, et al.Signaling Technology,4082 S,1:1000,0.03 TONSIL-2.1,18,5,CD4,Alexa 488,FITC,485,525,108,R&D Systems,FAB8165G,1:300,0.5 TONSIL-2.1,19,5,CD68,Alexa 555,Cy3,555,590,1,Cell Signaling Technology,79594 S,1:1000,0.5 TONSIL-2.1,20,5,CD20,Alexa

(8) Qualifying antibodies for image-based immune profiling and multiplexed tissue imagingNature ProtocolsOctober 1, 2019Ziming Du, Jia-Ren Lin, Rumana Rashid, Zoltan Maliga, Shu Wang, Jon C. Aster, Benjamin Izar, Peter K. Sorger, Sandro Santagata201825,100 3,CD45RB,PD7/26,eBioscience,53-9458-80,100,CD3,EP4426,Abcam,ab208514,100,PD-L1,E1L3N,CST,15005S,50 4,CD4,Polyclonal,R&D Systems,FAB8165G,100,CD45,2D1,R&D Systems,FAB1430P-025,100,CD8a,AMC908,eBioscience,50-0008-80,100 5,CD163,EPR14643,Abcam,ab218293,100,CD68,D4B9C,CST,#79594,100,CD14,EPR3653,Abcam,ab196169,100 6,CD11b,C67F154,eBioscience,53-0196-80,100,Foxp3,236A/E7,eBioscience,41-4777-80,100,,,,, 7,IBA1,EPR6136,Abcam,ab195031,250,α-SMA,EPR5368,Abcam,ab202509,250,CD20,L26,eBioscience,50-0202-80,250 8,CD19,EPR5906,Abcam,ab196468,100,GFAP,GA5,eBioscience,41-9892-80,100,,,,, t-CyCIF

(9) Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopeseLifeJuly 11, 2018Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.488,AB_2562171 CD11b-488,CD11b,*,Abcam,AB204271,EPR1344,Alexa Fluor 488, CD4-488,CD4,*,R and D Systems,FAB8165G,Polyclonal,Alexa Fluor 488, CD8a-488,CD8,*,eBioscience,53-0008-80,AMC908,Alexa Fluor 488,AB_2574412 cJUN-488,cJUN,*,Abcam,AB193780,E254,Alexa

(10) Accumulation of follicular CD8+ T cells in pathogenic SIV infectionThe Journal of clinical investigationMay 1, 2018Ferrando-Martinez S, Moysi E, Pegu A, Andrews S, Nganou Makamdop K, Ambrozak D, McDermott AB, Palesch D, Paiardini M, Pavlakis GN, et al.CD20–eFluor 615 (eBiosciences, catalog 42-0202-82, clone L26); and CD4-Ax488 (R&D Systems, catalog FAB8165G, goat polyclonal); and nonconjugated antibodies against CD3 (Dako, catalog M725401, clone F7.2.38);

(11) Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodesPLoS pathogensFebruary 1, 2018Watson DC, Moysi E, Valentin A, Bergamaschi C, Devasundaram S, Fortis SP, Bear J, Chertova E, Bess J Jr, Sowder R, et al.L26), anti-CD3 Alexa Fluor 680 or 594 (clone F7.2.38), anti-CD4 Alexa Fluor 488 (goat polyclonal IgG, FAB8165G, R&D systems), antiGranzyme B Alexa Fluor 647 or 680 (clone GrB-7), anti-Ki67 Brilliant Violet 421 or

(12) Quantitative Multiplexed Imaging Analysis Reveals a Strong Association between Immunogen-Specific B Cell Responses and Tonsillar Germinal Center Immune Dynamics in Children after Influenza VaccinationJournal of immunology (Baltimore, Md. : 1950)January 15, 2018Amodio D, Cotugno N, Macchiarulo G, Rocca S, Dimopoulos Y, Castrucci MR, De Vito R, Tucci FM, McDermott AB, Narpala S, et al.

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CD4 Alexa Fluor 488-conjugated Antibody

CD4 Alexa Fluor 488-conjugated Antibody

CD4 Alexa Fluor 488-conjugated Antibody

CD4 Alexa Fluor 488-conjugated Antibody

CD4 Alexa Fluor 488-conjugated Antibody

CD4 Alexa Fluor 488-conjugated Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (12)

Reviews

CD4 Alexa Fluor 488-conjugated Antibody from R&D Systems, a Bio-Techne Brand

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