Anti-CRBN antibody ab68763 from Abcam

Product Specs
ItemAnti-CRBN antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab68763
Antibody TypePrimary
IsotypeIgG
HostMouse, Nude mouse
Quantity50 UG
Conjugate/TagUnconjugated
ClonalityPolyclonal
ApplicationsWestern blot
Concentration0.5 mg/ml
Gene Namecrbn
ReactivityHuman, Recombinant fragment
TargetCRBN

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signalingNature communicationsSeptember 6, 2021Shen C, Nayak A, Neitzel LR, Adams AA, Silver-Isenstadt M, Sawyer LM, Benchabane H, Wang H, Bunnag N, Li B, et al.immunoprecipitation from HEK cells, the cell extracts were incubated with 1 μg of CRBN antibodies (Abcam ab68763) or PTEN antibodies (Santa Cruz Biotechnology sc-393186) overnight at 4 °C. Protein G agarose beads

(2) CRBN Is a Negative Regulator of Bactericidal Activity and Autophagy Activation Through Inhibiting the Ubiquitination of ECSIT and BECN1Frontiers in ImmunologySeptember 18, 2019Mi-Jeong Kim, Yoon Min, Jae-Hyuck Shim, Eunyoung Chun, Ki-Young Leeubiquitin ligase activity. Materials and Methods Antibodies and Reagents Antibodies Anti-CRBN (Ca# ab68763), anti-GRIM19 (Ca# ab134325), and anti-ECSIT (Ca# ab21288) were purchased from Abcam, Cambridge, MA,

(3) A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myelomaBlood AdvancesAugust 22, 2017Ajai Chari et al.with MAGE-A1 antibody (MA454, mouse monoclonal antibody; Santa Cruz Biotechnologies, sc20033), CRBN (Ab68763, mouse polyclonal; Abcam), Aiolos (D1C1E, rabbit polyclonal; Cell Signaling Technologies, 12720), Ikaros

(4) Measuring cereblon as a biomarker of response or resistance to lenalidomide and pomalidomide requires use of standardized reagents and understanding of gene complexityBritish journal of haematologyJanuary 1, 2014Gandhi AK, Mendy D, Waldman M, Chen G, Rychak E, Miller K, Gaidarova S, Ren Y, Wang M, Breider M, et al.generated the anti-CRBN monoclonal antibody CRBN65. Commercial CRBN antibodies used included Abcam ab68763 (Abcam 1) and ab98992 (Abcam 2); Aviva ARP56882_P050; Novus H00051185-B01P; ProteinTech 11435-1-AP;

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Anti-CRBN antibody from Abcam

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Anti-CRBN antibody from Abcam

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