DNA/RNA Damage Antibody (15A3) NB110-96878 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemDNA/RNA Damage Antibody (15A3)
CompanyNovus Biologicals, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberNB110-96878
Immunogen8-hydroxy-guanosine-BSA and-casein conjugates
Concentration1 mg/ml
FormatPBS, 50% Glycerol
ClonalityMonoclonal
ReactivityHuman, Mouse, Non-species specific
Clone15A3
Conjugate/TagUnconjugated
Quantity0.1 mg (also 0.025 mg)
IsotypeIgG2b
HostMouse
ApplicationsFlow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunoassay, Dot Blot, Functional Assay
TargetDNA/RNA Damage
Brand/TrademarkNovus Biologicals, a Bio-Techne Brand
PurityProtein G purified
Antibody TypePrimary Antibodies
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles

Specifications/Features

Available conjugates: Unconjugated

Specificity: Recognizes markers of oxidative damage to DNA (8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)

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Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: http://www.novusbio.com

(1) Development of a model for studying the developmental consequences of oxidative sperm DNA damage by targeting redox-cycling naphthoquinones to the Sertoli cell populationFree radical biology & medicineSeptember 1, 2023Fraser BA, Wilkins AL, De Iuliis GN, Rebourcet D, Nixon B, Aitken RJ.

(2) Conjunctival epitheliopathy induced by topical exposure to bacterial peptidoglycan, muramyl dipeptideExperimental eye researchFebruary 1, 2023Langford MP, Srur L, Redens TB, Byrd WA.

(3) Determination of Ram (Ovis aries) Sperm DNA Damage Due to Oxidative Stress: 8-OHdG Immunodetection Assay vs. SCSA(®)Animals : an open access journal from MDPINovember 25, 2022Soria-Meneses PJ, Jurado-Campos A, Gómez-Rubio V, Sánchez-Ajofrín I, Soler AJ, Garde JJ, Fernández-Santos MDR.monoclonal anti-8-OHdG antibody (mouse anti-8-OHdG monoclonal antibody DNA/RNA damage antibody-15A, NB110-96878, Novus Biologicals®, Lille, France), Alexa Fluor™ 488 goat anti-mouse antibody (Fisher Scientific, Madrid,

(4) Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stressScience advancesOctober 7, 2022Shrestha S, Erikson G, Lyon J, Spigelman AF, Bautista A, Manning Fox JE, Dos Santos C, Shokhirev M, Cartailler JP, Hetzer MW, et al.[rabbit, Bethyl Laboratories (catalog no. IHC-0001) at 1:100], 8HG [rabbit, Novus Biologicals (catalog no. NB110-96878) at 1:100], NKX6.1 [rabbit, Cell Signaling Technology (catalog no. D8O4R) at 1:100 dilution], NKX2.2

(5) Apoptotic M540 bodies present in human semen interfere with flow cytometry-assisted assessment of sperm DNA fragmentation and oxidationBasic and clinical andrologyOctober 21, 2021Sadeghi N, Tavalaee M, Kiani-Esfahani A, Moazamian A, Gharagozloo P, Aitken RJ, Drevet JR, Nasr-Esfahani MH.Temecula, CA, USA). The samples were then incubated overnight with an anti-8-OHdG monoclonal antibody (NB110–96878, Novus Biologicals, The Netherlands) at a dilution of 1:1500 and, subsequently, with a secondary antibody

(6) Oxidative Stress Is Associated with Telomere Interaction Impairment and Chromatin Condensation Defects in Spermatozoa of Infertile MalesAntioxidants (Basel, Switzerland)April 12, 2021Berby B, Bichara C, Rives-Feraille A, Jumeau F, Pizio PD, Sétif V, Sibert L, Dumont L, Rondanino C, Rives N.5% (w/v) BSA, clone 15A3, Novus Biologicals, Littleton, 8-OHdG IgGs (2 µg/mL in PBS + 5% (w/v) BSA,NB110-96878, clone 15A3, NB110-96878, Novus BiologiCO, USA). Slides were then rinsed three times in PBS with Tween 20% (Sigma-Aldrich cals,

(7) Melatonin alleviates heat stress-induced oxidative stress and apoptosis in human spermatozoaFree radical biology & medicineFebruary 20, 2021Zhao F, Whiting S, Lambourne S, Aitken RJ, Sun YP.

(8) Three-Dimensional Confocal Analysis of Chromosome Positioning Coupled with Immunofluorescence in Mouse Sperm NucleiMethods in molecular biology (Clifton, N.J.)January 1, 2021Champroux A, Goubely C, Henry-Berger J, Drevet JR, Kocer A.

(9) Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in AutoimmunityCell metabolismOctober 6, 2020Alissafi T, Kalafati L, Lazari M, Filia A, Kloukina I, Manifava M, Lim JH, Alexaki VI, Ktistakis NT, Doskas T, et al.

(10) A novel pathway for the induction of DNA damage in human spermatozoa involving extracellular cell-free DNAMutation researchMay 1, 2020Aitken RJ, Whiting S, Connaughton H, Curry B, Reinheimer T, van Duin M.

(11) The Exacerbation of Aging and Oxidative Stress in the Epididymis of Sod1 Null MiceAntioxidants (Basel, Switzerland)February 11, 2020Noblanc A, Klaassen A, Robaire B.Antibodies,Primary Antibodies 8-OHG (DNA/RNA),None,Mouse Monoclonal (15A3),1/1000,Novus Biologicals,NB110-96878 4-HNE,None,Rabbit polyclonal,1/500,Abcam,ab46545 "SRC, C-term",None,Mouse monoclonal,1/250,Santa Cruz,sc8056 Secondary

(12) Ovine sperm DNA oxidation quantification using an 8-OHdG immunodetection assayReproduction in domestic animals = ZuchthygieneOctober 1, 2019Soria-Meneses PJ, Jurado-Campos A, Montoro V, Soler AJ, Garde JJ, Fernández-Santos MDR.

(13) Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in miceReproduction (Cambridge, England)August 1, 2019Youngson NA, Uddin GM, Das A, Martinez C, Connaughton HS, Whiting S, Yu J, Sinclair DA, Aitken RJ, Morris MJ.

(14) Accuracy of human sperm DNA oxidation quantification and threshold determination using an 8-OHdG immuno-detection assayHuman reproduction (Oxford, England)April 1, 2018Vorilhon S, Brugnon F, Kocer A, Dollet S, Bourgne C, Berger M, Janny L, Pereira B, Aitken RJ, Moazamian A, et al.

(15) Improved methods of DNA extraction from human spermatozoa that mitigate experimentally-induced oxidative DNA damagePloS oneJanuary 1, 2018Xavier MJ, Nixon B, Roman SD, Aitken RJ.

(16) Assessment of sperm nuclear quality after in vitro maturation of fresh or frozen/thawed mouse pre-pubertal testesMolecular human reproductionOctober 1, 2017Oblette A, Rives N, Dumont L, Rives A, Verhaeghe F, Jumeau F, Rondanino C.

(17) Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant micePloS oneJanuary 1, 2012Noblanc A, Peltier M, Damon-Soubeyrand C, Kerchkove N, Chabory E, Vernet P, Saez F, Cadet R, Janny L, Pons-Rejraji H, et al.

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DNA/RNA Damage Antibody (15A3)

DNA/RNA Damage Antibody (15A3)

DNA/RNA Damage Antibody (15A3)

DNA/RNA Damage Antibody (15A3)

DNA/RNA Damage Antibody (15A3) from Novus Biologicals, a Bio-Techne Brand

Specifications/Features

Novus Biologicals, a Bio-Techne Brand

Citations (17)

Reviews

DNA/RNA Damage Antibody (15A3) from Novus Biologicals, a Bio-Techne Brand

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