Brilliant Violet 711(TM) anti-human CD4 317440 from BioLegend

Product Specs
ItemBrilliant Violet 711(TM) anti-human CD4
CompanyBioLegend
Price Pricing Info Supplier Page View Company Product Page
Catalog Number317440
Quantity100 tests
ApplicationsFlow Cytometry (FC)
Conjugate/TagBrilliant Violet 711™
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
ReactivityHuman, Cynomolgus, Rhesus
IsotypeIgG2b, Kappa
CloneOKT4
HostMouse
Antibody TypePrimary
NCBI Full Gene NameCD4 molecule
NCBI Gene AliasesCD4mut, IMD79, Leu-3, OKT4D, T4
ClonalityMonoclonal
ImmunogenHuman peripheral T cells
TargetCD4

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodiesCell reportsMarch 28, 2023Hora B, Li H, Shen X, Martin M, Chen Y, Berry M, Evangelous T, Macintyre AN, Arus-Altuz A, Wang S, et al.RRID:AB_2563807 BV786 anti-human CD45RA,BD,Cat# 741010; RRID:AB_2740633 Alexa Fluor 700 anti-human CD4,BioLegend,Cat# 317440; RRID:AB_2562912 APC-Cy7 anti-human CD3,BD,Cat# 557757; RRID:AB_396863 BB515 anti-human ICOS,BD,Cat#

(2) Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibodyOncoimmunologyNovember 10, 2022Jessica D. Weaver, Edward C. Stack, Joshua A. BuggÃ©, Changyun Hu, Lara McGrath, Amy Mueller, Masie Wong, Boris Klebanov, Tanzila Rahman, Rosemary Kaufman, et al.L34976), CD45-BUV396 (BD Biosciences, 563792), CD3-AF488 (Biolegend, 300320), CD4-BV711 (Biolegend, 317440), CD56-PE (BD Biosciences, 555516), and FOXP3-BV421 (Biolegend, 320124). Treg killing was assessed by

(3) Early treatment regimens achieve sustained virologic remission in infant macaques infected with SIV at birthNature CommunicationsAugust 16, 2022Xiaolei Wang et al.700 (clone SP34-2, Cat No: 557917, Lot No: 0293255), CD4-Brilliant Violet 711 (clone OKT4, Cat No: 317440, Lot No: B293041, BioLegend), CD8-APC-H7 (clone SK1, Cat No: 560179, Lot No: 1039448), CD8-PE (clone

(4) A humanized mouse model of chronic COVID-19Nature BiotechnologyJune 1, 2022Esen Sefik et al.Biolegend 304610 1:100; CD56(MEM-188) Pacific Blue Biolegend 304629 1:50; CD4(OKT4) BV711 Biolegend 317440 1:100; CD8(SK1) Pacific Blue Biolegend 344718 1:100; CD8(SK1) BV421 Biolegend 344748 1:200; TCRGD(B1)

(5) SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humansCellFebruary 17, 2022Mudd PA, Minervina AA, Pogorelyy MV, Turner JS, Kim W, Kalaidina E, Petersen J, Schmitz AJ, Lei T, Haile A, et al.HI100),BioLegend,cat#: 304130; RRID: AB_10965547 CD4 BV711 (clone OKT4),CD4 BV711 (clone OKT4),BioLegend,cat#: 317440; RRID: AB_2562912 CD3 PerCP-Cy5.5 (clone OKT3),CD3 PerCP-Cy5.5 (clone OKT3),BioLegend,cat#: 317336;

(6) Nanocages engineered from Bacillus Calmette-Guerin facilitate protective Vγ2Vδ2 T cell immunity against Mycobacterium tuberculosis infectionJournal of nanobiotechnologyJanuary 15, 2022Pi J, Zhang Z, Yang E, Chen L, Zeng L, Chen Y, Wang R, Huang D, Fan S, Lin W, et al.CD161-BV510 antibody (Biolegend, Catalog No. 339922), anti-human CD4-BV711 antibody (Biolegend, Catalog No. 317440), anti-human TNF-a-BV605 antibody (Biolegend, Catalog No. 502936), anti-human NKG2C lgG antibody (Miltenyi Biotec

(7) Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling DomainsHuman Gene TherapyOctober 18, 2021Ali Can Sahillioglu, Ton N. Schumacher0.5% BSA) and stained with anti-CD8-PerCP Cy5.5 (No. 341050, 1:20 dilution; BD), anti-CD4 BV711 (No. 317440, 1:50 dilution; Biolegend), anti-murine constant TCR-PE (in experiments using TCR transduced T cells,

(8) CRASH-IT Switch Enables Reversible and Dose-Dependent Control of TCR and CAR T-cell FunctionCancer immunology researchSeptember 1, 2021Sahillioglu AC, Toebes M, Apriamashvili G, Gomez R, Schumacher TN.dilution, BD Biosciences, catalog no. 341050), anti-CD4 BV711 (1:50 dilution, BioLegend, catalog no. 317440), anti-murine constant TCR-PE (in experiments using TCR-transduced T cells, 1:200 dilution, BD Biosciences,

(9) Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitorsScientific reportsJuly 28, 2021Dart SJ, Cook AM, Millward MJ, McDonnell AM, Chin WL, Hakeem MU, Meniawy TM, Bowyer SE.(ThermoFisher), plus antibodies against CD3-BV510 (BD, UCHT1, 563109), CD4-BV711 (BioLegend, OKT4, 317440), CD8a-eVolve605 (ThermoFisher, RPA-T8, 83–0088-42), CD14-APC-eF780 (ThermoFisher, 61D3, 47-0149-42),

(10) Stage-Dependent Within-Individual Comparison Reveals SIV-Specific Activation/Exhaustion Shift in Rhesus MacaquesFrontiers in MicrobiologyJuly 19, 2021Ling Tong, Zhe Cong, Long Tian, Jingjing Zhang, Jiahan Lu, Qiuhan Lu, Ting Chen, Yuhong Wang, Qiang Wei, Jing Xuewere stained with anti-CD3 BV605 (SP34-2, BD Biosciences, 562994), anti-CD4 BV711 (OKT-4, Biolegend, 317440), anti-CD8 PE (RPA-T8, BD Biosciences, 557086), anti-CCR7 BV421 (G043H7, Biolegend, 352208), anti-CD45RA

(11) Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cellsImmunityApril 13, 2021Delacher M, Simon M, Sanderink L, Hotz-Wagenblatt A, Wuttke M, Schambeck K, Schmidleithner L, Bittner S, Pant A, Ritter U, et al.

(12) MAIT cell activation is associated with disease severity markers in acute hantavirus infectionCell reports. MedicineMarch 16, 2021Maleki KT, Tauriainen J, García M, Kerkman PF, Christ W, Dias J, Wigren Byström J, Leeansyah E, Forsell MN, Ljunggren HG, et al.conjugated,BioLegend,"Cat#301038, clone RPA-T8, RRID: AB_2563213" Mouse monoclonal anti-CD4 BV711 conjugated,BioLegend,"Cat#317440, clone GB11, RRID: AB_2562912" Mouse monoclonal anti-IFN-γ BV785 conjugated,BioLegend,"Cat#502542,

(13) Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19CellJanuary 7, 2021Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, et al.G043H7",BioLegend,Cat #353224; RRID: AB_2561753 "Anti-human CD4-BV711, Clone OKT4",BioLegend,Cat #317440; RRID: AB_2562912 "Anti-human CD127-BV786, Clone hIL7Rm21",BD,Cat #563324; RRID: AB_2738138 "Anti-human

(14) T cells drive negative feedback mechanisms in cancer associated fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancerOncoimmunologyJanuary 1, 2021O'Connor RA, Chauhan V, Mathieson L, Titmarsh H, Koppensteiner L, Young I, Tagliavini G, Dorward DA, Prost S, Dhaliwal K, et al.RRID:AB_2629584 Clone SK1" "Brilliant Violet 711™ anti-human CD4 antibody, BioLegend",Biolegend,"BioLegend Cat# 317440, RRID:AB_2562912 Clone OKT4" APC anti-human CD103 (Integrin alphaE) antibody,Biolegend,"BioLegend Cat#

(15) Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus MacaquesCellOctober 1, 2020Alter G, Yu WH, Chandrashekar A, Borducchi EN, Ghneim K, Sharma A, Nedellec R, McKenney KR, Linde C, Broge T, et al.CD66b Antibody,Biolegend,CAT# 305112 Brilliant Violet 711™ anti-human CD4 Antibody,Biolegend,CAT #: 317440 Clone: OKT4 Alexa Fluor® 700 Mouse Anti-Human CD3,BD Biosciences,CAT#: 557917 Clone: SP34 APC/Cyanine7

(16) Immune checkpoint modulation enhances HIV-1 antibody inductionNature communicationsFebruary 19, 2020Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, et al.anti-human CD25 (clone BC96; Biolegend #302634; 1:50), BV711 anti-human CD4 (clone OKT4; Biolegend #317440; 1:50), and BV785 anti-human CD20 (clone 2H7; Biolegend #302356; 1:50). Cells were then incubated with

(17) Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope ImmunizationCell reportsFebruary 4, 2020Han Q, Bradley T, Williams WB, Cain DW, Montefiori DC, Saunders KO, Parks RJ, Edwards RW, Ferrari G, Mueller O, et al.BC96",Biolegend,Cat# 302634; RRID:AB_2563807 "Mouse anti-Human CD4 Brilliant Violet 711, Clone OKT4",Biolegend,Cat# 317440; RRID:AB_2562912 "Mouse anti-Human CD45RA Brilliant Violet 786, Clone 5H9",BD Biosciences,Cat# 741010;

(18) Unique T-Cell Populations Define Immune-Inflamed Hepatocellular CarcinomaCellular and molecular gastroenterology and hepatologyJanuary 1, 2020Di Blasi D, Boldanova T, Mori L, Terracciano L, Heim MH, De Libero G.γδ,Brilliant Violet 421,Mouse,Human,B1,Biolegend,331218 CD4,Brilliant Violet 711,Mouse,Human,OKT4,Biolegend,317440 HLA-DR,Alexa Fluor 700,Mouse,Human,L243,Biolegend,307626 CD38,Brilliant Violet 650,Mouse,Human,HB-7,Biolegend,356620 CD137,PE/Dazzle

(19) Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic PathwaysCellNovember 14, 2019Huang B, Chen Z, Geng L, Wang J, Liang H, Cao Y, Chen H, Huang W, Su M, Wang H, et al.

(20) Primary HIV-1 Strains Use Nef To Downmodulate HLA-E Surface ExpressionJournal of virologyOctober 15, 2019van Stigt Thans T, Akko JI, Niehrs A, Garcia-Beltran WF, Richert L, Stürzel CM, Ford CT, Li H, Ochsenbauer C, Kappes JC, et al.

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(1)

9/27/2016CD4 Antibody That Works, Nothing Special Though Brahma KumarThis antibody gives clear separation but is not as bright as I would expect from a BV711 color. Easy to use, works well at 1:50

Brilliant Violet 711(TM) anti-human CD4 from BioLegend

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Brilliant Violet 711(TM) anti-human CD4 from BioLegend

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