Fig 2: Correlation between ADH1B expression and ADH1B methylation. The expression of the ADH1B gene is negatively correlated with ADH1B methylation.

Fig 3: Drug sensitivity analysis of ADH1B. Scatter plots of correlation analysis between ADH1B and drugs (panobinostat, oxaliplatin, ixabepilone, and seliciclib).

Fig 4: Potential regulatory pathways of ADH1B. (A) Differential enriched KEGG pathways between ADH1B-higher-expression group and ADH1B-lower-expression group. (B) GSEA showed significant enriched hallmark terms between higher ADH1B and lower ADH1B groups. (C) Scatter plots of correlation analysis between the CCP score and ADH1B. (D) Scatter plots of correlation analysis between G1/S cell cycle and ADH1B. (E) Scatter plots of correlation analysis between G2M Checkpoint and ADH1B. (F) Scatter plots of correlation analysis between inflammation pathways and ADH1B.

Fig 5: Identification of key genes based on immune abnormalities. (A, B) Among eight candidate genes, ADH1B was negatively correlated with the immune score. (C) ADH1B was significantly correlated with some immune cells among 28 immune cells. (D) Correlation heatmap displayed ADH1B correlated with several immune cells among 22 immune cells.