Anti-C5a-R antibody ab59390 from Abcam

Product Specs
ItemAnti-C5a-R antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab59390
Antibody TypePrimary
ApplicationsELISA, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
ClonalityPolyclonal
IsotypeIgG
Quantity100 UG
HostRabbit
Conjugate/TagUnconjugated
FormatThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Concentration1 mg/ml
Research AreaImmuno-oncology
Gene NameC5AR1
ReactivityHuman
TargetC5a-R

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Xuanfei Baidu Decoction suppresses complement overactivation and ameliorates IgG immune complex-induced acute lung injury by inhibiting JAK2/STAT3/SOCS3 and NF-κB signaling pathwayPhytomedicine : international journal of phytotherapy and phytopharmacologyJanuary 1, 2023Li C, Li Y, Zhang H, Zhuo Y, Zhang L, Yang L, Gao Q, Tu Z, Shao R, Wang Y, et al.were purchased from Novus Biologicals (Littleton, CO, United States). Anti-C5a (ab194637), anti-C5aR (ab59390) and IL-1β (ab254360) were obtained from Abcam (Cambridge, MA, United States). Anti-p-JAK2 (3771s),

(2) Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cellsJournal of neuroinflammationJuly 14, 2022Llorián-Salvador M, Byrne EM, Szczepan M, Little K, Chen M, Xu H.conjugated),C6198,Sigma-Aldrich,Mouse Rabbit anti-α-SMA,ab5694,Abcam,Rabbit C5b-9,ab65811,Abcam,Rabbit C5aR,ab59390,Abcam,Rabbit C5aR,ab117579,Abcam,Rat C5R1 Biotin,ab54378-100,Abcam,Biotin C5a antibody (FITC),orb360860,Biorbyt,Rat C5a antibody

(3) Recruitment of IL ‐1β‐producing intermediate monocytes enhanced by C5a contributes to the development of malignant pleural effusionThoracic CancerMarch 1, 2022Lisha Luo, Shuanglinzi Deng, Wei Tang, Xinyue Hu, Feifei Yin, Huan Ge, Jiale Tang, Zhonghua Liao, Xiaozhao Li, Juntao Fengincluding C5a (ab11877, Abcam), CCL2 (MABN712, Millipore), and rabbit anti‐human antibodies, such as C5aR1 (ab59390, Abcam), CCR2(NBP1‐48337, Novusbio)) by the manufacturer. After washing, slides were incubated with

(4) CRP immunodeposition and proteomic analysis in abdominal aortic aneurysmPLOS ONEAugust 24, 2021Eun Na Kim, Jiyoung Yu, Joon Seo Lim, Hwangkyo Jeong, Chong Jai Kim, Jae-Sung Choi, So Ra Kim, Hee-Sung Ahn, Kyunggon Kim, Se Jin Ohincluding C1q (ab75756, Abcam), C3a (LS-B15388, LSBio, Seattle, USA), C5a (ab193295, Abcam), and C5a R (ab59390, Abcam). For secondary antibody, the Optiview DAB IHC Detection Kit (Ventana medical systems) was used.

(5) Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder SubjectsInternational Journal of Molecular SciencesJuly 15, 2021Fernanda Mansur, André Luiz Teles e Silva, Ana Karolyne Santos Gomes, Juliana Magdalon, Janaina Sena de Souza, Karina Griesi-Oliveira, Maria Rita Passos-Bueno, Andréa Laurato Sertiénonspecific bands on western blots using total protein from NPC, neuron or astrocyte lysates: ab126250, ab59390 and ab134918 (Abcam), respectively. Detection was performed using horseradish peroxidase-coupled anti-rabbit

(6) Anaphylatoxins orchestrate Th17 response via interactions between CD16+ monocytes and pleural mesothelial cells in tuberculous pleural effusionPLoS neglected tropical diseasesJuly 1, 2021Deng S, Hu X, Luo L, Tang W, Jiang Y, Yin F, Hu C, Feng J, Li X.Abcam), rabbit anti-human C3aR1(NBP2-15649, Novusbio) antibody and rabbit anti-human C5aR1 antibody (ab59390, Abcam) and diluted to the manufacturers’ recommended concentrations and applied for overnight incubation

(7) Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient MiceFrontiers in physiologyJanuary 1, 2020Asare Y, Koehncke J, Selle J, Simsekyilmaz S, Jankowski J, Shagdarsuren G, Gessner JE, Bernhagen J, Shagdarsuren E.Heidelberg, Germany), myeloperoxidase (MPO, RB-373-A, Neomarkers, Freemont, CA, United States), C5aR1 (CD88, ab59390, Abcam, Cambridge, United Kingdom), α-SMA (M0851, Dako, Hamburg, Germany), Mac-2 (CL8942AP, CEDARLANE,

(8) C5aR1 interacts with TLR2 in osteoblasts and stimulates the osteoclast-inducing chemokine CXCL10Journal of cellular and molecular medicineDecember 1, 2018Mödinger Y, Rapp A, Pazmandi J, Vikman A, Holzmann K, Haffner-Luntzer M, Huber-Lang M, Ignatius A.RT. Cells were permeabilized with 0.1% Triton X‐100 before incubation with rabbit C5aR1 antibody (#ab59390, 1:100, Abcam, Cambridge, UK), rabbit TLR2 antibody (#bs‐1019R, 1:100, Bioss) or rabbit IgG antibody

(9) Myocardial expression of the anaphylatoxin receptor C3aR is associated with cardiac inflammation and prognosis in patients with non-ischaemic heart failureESC Heart FailureOctober 1, 2018Karin A.L. Mueller et al.antibody (H‐300; sc‐20138, Santa Cruz Biotechnology, Santa Cruz, CA, USA) or a C5aR antibody (anti‐C5R1, ab59390, Abcam, Cambridge, UK) followed by a biotinylated secondary antibody mix (‘Biotinylated Link Universal’,

(10) Panton–Valentine Leukocidin Colocalizes with Retinal Ganglion and Amacrine Cells and Activates Glial Reactions and Microglial ApoptosisScientific ReportsFebruary 13, 2018XuanLi Liu, Pauline Heitz, Michel Roux, Daniel Keller, Tristan Bourcier, Arnaud Sauer, Gilles Prévost, David Gaucher

(11) Antagonist of C5aR prevents cardiac remodeling in angiotensin II-induced hypertensionAmerican journal of hypertensionJune 1, 2014Congcong Zhang, Yulin Li, Chunxiao Wang, Yina Wu, Jie Du

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Anti-C5a-R antibody from Abcam

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Anti-C5a-R antibody from Abcam

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