Description
Product Characteristics:
EphA3 is a member of the Ephrin (Eph) family. The Ephrins and Eph-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the Ephrin A (EphA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the Ephrin B (EphB) class, which are transmembrane proteins. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats.
Subcellular location: Secreted, Cell membrane
Synonyms: EPH A3+A4+A5 phospho Y779, p-EPH A3+A4+A5 phospho Y779, CEK7, EHK 1, EHK1, EK4, EK7, EK8, EPH homology kinase 1, EPH like kinase 4, EPH like kinase 7, EPH like kinase 8, Eph like tyrosine kinase 1, EPH receptor A3, EPH receptor A4, EPH receptor A5, Ephrin type A receptor 3, Ephrin type A receptor 4, Ephrin type A receptor 5, ETK, ETK1, HEK, HEK4, HEK7, HEK8, Human embryo kinase 1, Receptor protein tyrosine kinase HEK7, Receptor protein tyrosine kinase HEK8, SEK, TYRO1, TYRO1 protein tyrosine kinase, TYRO4, TYRO4 protein tyrosine kinase, Tyrosine protein kinase receptor EHK 1, Tyrosine protein kinase receptor ETK1, Tyrosine protein kinase receptor SEK, Tyrosine protein kinase TYRO1, EPHA3_HUMAN, EPHA4_HUMAN, EPHA5_HUMAN.
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