Description
Product Characteristics:
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Subcellular location: Cell membrane
Synonyms: carcinoembryonic, Carcinoembryonic antigen CGM1, carcinoembryonic antigen related cell adhesion molecule 3, Carcinoembryonic antigen-related cell adhesion molecule 3, cd66 d, CD66d, CEA, CEACAM 3, CEACAM-3, Ceacam3, CEAM 3, CEAM-3, CEAM3, CEAM3_HUMAN, CGM1, W264, W282.
Target Information: This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]