Description
Product Characteristics:
The RING finger family of proteins possess ubiquitin ligase activity and play pivotal roles in protein degradation and receptor-mediated endocytosis. The autoubiquitination activity of ZNF364 indicates that it is a novel RING-type E3 ligase. Its effects on cell growth indicate that ZNF364 may be important for the ubiquitin modification of proteins crucial to breast carcinogenesis and growth.
Subcellular location: Cytoplasm
Synonyms: BCA2, Breast cancer associated gene 2, CL469780, Rabring 7, RING finger protein 115, RNF115, Zinc finger protein 364, RN115_HUMAN.
Target Information: Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking