Description
Product Characteristics:
This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons
Subcellular location: Nucleus
Synonyms: B-cell oct-binding protein 1, B-cell-specic coactivator OBF-1, POU domain class 2-associating factor 1, POU2AF1, OCT-binding factor 1, BOB-1, OCA-B. OBF1, OCA-B, OBF1_HUMAN.
Target Information: Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers