Description
Product Characteristics:
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 2 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations, however, cortisol, testosterone and dopamine are not sulfated.
Subcellular location: Cytoplasm
Synonyms: EST, STE, EST-1, ST1E1, Estrogen sulfotransferase, Sulfotransferase 1E1, Sulfotransferase, estrogen-preferring, SULT1E1
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information