Description
Product Characteristics:
Broad range protease inhibitor.
Subcellular location: Secreted
Synonyms: HE4, WAP5, 1600023A02Rik, WAP four-disulfide core domain protein 2, WAP domain-containing protein HE4, Wfdc2
Target Information: This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]